More questions Flashcards
Name 2 drugs licensed for post-exposure prophylaxis for influenza and can they be used seasonally?
Oseltamivir (Tamiflu)
Zanamivir (Relenza)
No neither is recommended for seasonal prophylaxis against influenza
What is a black triangle medicine?
A newly licensed medication which requires additional monitoring by the European Medicines Agency
This will retain a black triangle for 5 years, but this can be extended if required
Who should not be given Tetracyclines?
Pregnant women
Breast feeding women
Children < 12 years
An antibiotic is prescribed for an oral infection and patients condition does not improve, when should an alternative antibiotic be prescribed?
After 48 hrs, preferably on the basis of bacteriological investigation
Give some examples of Dematological Proceedures.
Excision of moles
Excision of malignant lesions
Skin biopsy
Are penicillins bactericidal or bacteriostatix ?
Bactericidal – they interfere with cell wall synthesis
Which combination of drugs can be used in severe/resistant oral infections?
Penicillin or a Macrolide
+ Metronidazole
What is a notifiable disease?
A disease for which doctors must notify the Proper Officer of the local authority (usually the consultant in communicable disease control) when dealing with a patient suffering from those listed
Examples:
Anthrax | Malaria | Plague | Food poisoning
Which antibiotic is used for the prevention of secondary cases of haemophilus influenza type B disease in adults and children?
Rifampicin
- child 1 - 2 months (10 mg/kg OD for 4 days)
- child 3 months to 11 yrs (20 mg/kg OD for 4 days, max 600 mg/dose)
- child 12+/adult (600 mg OD for 4 days)
What Is the active ingredient in Xalantan?
latanoprost
For the treatment of glaucoma
What is the active ingredient in Timoptol?
Timolol
For the treatment of glaucoma
What is the active ingredient in Betoptic?
Betaxolol
For the treatment of glaucoma
Who is more likely to suffer with cholestatic jaundice caused by co-amoxiclav?
Patients over 65 and male
Jaundice is usually self limiting and very rarely fatal
Never the less, treatment should be appropriate for the indication And should NOT EXCEED 14 DAYS
Does a patient considered at risk of infective endocarditis need antibiotic prophylaxis for a skin biopsy?
No
Patients who undergo dermatological procedure DO NOT require antibacterial prophylaxis against endocarditis
What is the active ingredient in Cozaar?
Losartan
What is the active ingredient in Dequacaine?
Benzocaine and Dequalirium
What is the active ingredient in Proctosedyl?
Cinchocaine and hydrocortisone
What is the active ingredient in Merocaine?
Benzocaine and cetylpyridinium
What is the active ingredient in Cardarone X?
Amiodarone
Indicated in the treatment of arrhythmias
What is the active ingredient in Trandate?
Labetalol
What is the active ingredient in Cardura?
Doxazosin
What is the active ingredient in Zestril?
Lisinopril
Which antibiotic may cause cholestatic jaundice and hepatitis several weeks after stopping?
Flucoxacillin
May occur very rarely up to 2 months after treatment has been stopped
- administration for more than 2 weeks and increased age are a risk factor
N|B: not to be used in patients with:
- hepatic dysfunction
- hepatic impairment
- penicillin allergic
Is phenoxymethyl penicillin (penicillin V) given orally?
Yes
It is gastric acid stable therefore suitable for oral administration
What is the active ingredient in Trusopt?
Dorzolamide
For glaucoma
What is the active ingredient in Pariet?
Rabeprazole
Incubation periods of infectious illnesses in children
Slapped cheek Whooping cough Measles Chicken pox Mumps German measles(rubella)
Slapped cheek disease: 1-20 days
Whooping cough: 6-21 days
Measles: 7-12 days
Chicken pox : 1-3 weeks
Mumps: 14-25 days
German measles (rubella): 15-20 days
How do PPI’s work?
By blocking the hydrogen potassium adenosine triphosphate enzyme systemnof the gastric parietal cells
Yellow Cards what to report
All suspected adverse drug reactions that are:
- serious, medically significant or result in harm. Serious events are fatal, life-threatening, a congenital abnormality, disabling or incapacitating, or resulting in hospitalisation
- associated with newer drugs and vaccines (▼), irrespective of whether they are serious or not
