more passmed

Question 1

what drug can cause renal failure in patients with myeloma

Answer 1

NSAIDs

Question 2

how often should people with sickle cell get the pneumococcal vaccine

Answer 2

every 5 years

Question 3

treatment for neutropenic sepsis

Answer 3

Piperacillin with tazobactam (Tazocin)

Question 4

first line treatment for CML

Answer 4

imatinib

Question 5

if someone has suspected DVT, high D-dimer and then put on a DOAC, but then the leg USS is negative what do you do

Answer 5

stop anticoagulation and repeat ultrasound in 6-8 days

Question 6

tear drop poikilocytes

Answer 6

MYELOFIBROSIS

Question 7

reversal of rivaroxaban and apixaban

Answer 7

andexanet alpha

Question 8

what does isolated rise in GGT in the context of macrocytic anaemia suggest

Answer 8

alcoholism

Question 9

most common type of lymphoma in UK

Answer 9

diffuse large B cell

Question 10

rouleaux formation

Answer 10

myeloma

Question 11

normocytic anaemia, jaundice, raised reticulocytes and raised LDH

Answer 11

autoimmune haemolytic anaemia

Question 12

asymmetric spreading lymphadenopathy

Answer 12

Hodgkin’s lymphoma

Question 13

auer rods

Answer 13

AML

Question 14

smear/smudge cells

Answer 14

CLL
-due to abnormally fragile lymphocytes on the slide
-Crushed Little Lymphocytes

Question 15

what cancer is associated with polycythaemia rubra vera

Answer 15

AML

Question 16

A normocytic anaemia with low serum iron, low TIBC but raised ferritin

Answer 16

anaemia of chronic disease

Question 17

DIC blood picture

Answer 17

↓ platelets
↓ fibrinogen
↑ PT & APTT
↑ fibrinogen degradation products

Question 18

rivaroxaban MoA

Answer 18

direct factor Xa inhibitor

Question 19

what is hypertonic saline

Answer 19

saline with more sodium in it
-used for hyponatraemia (<120)

Question 20

first line investigation for placenta praevia

Answer 20

TVUS

Question 21

INR target range for being on warfarin for AF

Answer 21

2-3

Question 22

what antiplatelet medication is given post stroke and for how long (and doses)

Answer 22

ASPIRIN 300mg daily for two weeks
clopidogrel 75mg daily lifelong

Question 23

what kind of hernia is inferior and lateral to the pubic tubercle

Answer 23

femoral

Question 24

when would you do EVAR for an AAA

Answer 24

-if its symptomatic
-if its above 5.5cm
-if it enlarges more than 1cm/year

Question 25

what do u do if AAA 4.5-5.4cm

Answer 25

rescan every 3 months (if no symptoms)

Question 26

3-4.4cm AAA when do you scan

Answer 26

yearly

Question 27

if you find an asymptomatic AAA thats <3cm what do you do

Answer 27

nothing

Question 28

when do you excise a fibroadenoma

Answer 28

if its over 3 cm

Question 29

acute pericarditis ECG changed

Answer 29

saddle-shaped ST ELEVATION

Question 30

Afro-Caribbean patients with heart failure who are not responding to ACE-inhibitor, beta-blocker and aldosterone antagonist therapy - next step

Answer 30

Hydrazine and nitrate

Question 31

what are some complications of subclinical hyperthyroidism

Answer 31

-osteoporosis -atrial fibrillation -dementia

Question 32

which stroke causes ipsilateral CNIII palsy and contralateral hemiparesis

Answer 32

posterior cerebral artery (weber's syndrome

Question 33

LP fluid analysis in GBS

Answer 33

raised protein normal white cells

Question 34

what muscles are typically spared in MND

Answer 34

eye muscles

Question 35

what drugs exacerbate myasthenic crisis

Answer 35

penicillamine quinidine, procainamide beta-blockers lithium phenytoin antibiotics: gentamicin, macrolides, quinolones, tetracyclines

Question 36

first line investigation for carotid artery stenosis

Answer 36

duplex USS

Question 37

where is wernicke's area

Answer 37

superior temporal gyrus

Question 38

where is broca's area

Answer 38

inferior frontal gyrus