Mood disorders: depression Flashcards
depressive disorders
disturbance in psychological, physiological and social functioning
what are the symptoms associated with depressive disorders that disturb daily patterns
- sleep, appetite, ADLs, weight, attention, memory, libido
- impulse control, suicidal ideation, social withdraw
- physical symptoms: H/A, stomachache, muscle tension
levels of depression
transient depression
depressive disorder
transient depression
- a normal reaction to loss
- sadness directly attributable to a situation or disappointment - reactive or secondary depression
depressive disorder
- a sad mood related to external events or not
- symptoms range with dissatisfaction with life to sudden and abrupt changes to function that suppress or take away the will to live
incidence and prevalence
- major depression is most common
- affects all ages and backgrounds
- currently leading cause of disability in U.S. in age range 15-44 and projected to be the 2nd leading cause of disability for all ages by 2020
- affects 14.8 million people aged 18 years or older (6.7% of the population)
- average age: 32 years old
what is the most common illness of medical or psych
MAJOR DEPRESSION
what % of population experience major depressive disorder die from suicide
15%
prevalence in pre-puberty, adolescents, elderly community, nursing home
respectively 1-2% 3-8% 3.5% 15-20%
what group is depression a major health problem for
ELDERLY
why is depression a major health problem for older adults/elderly
- its difficult due to comorbid physical diseases (heart, DM)
- due to social limitations, losses, physical limits, HCP frequently conclude incorrectly that depression is a normal consequence of getting old
frequently accompanies other psych disorders
- schizophrenia
- substance abuse
- eating disorders
- anxiety problems
- personality disorders
risk factors for depressive disorders
- higher in women than men
- past episodes of depression
- family history
- stressful life event
- current substance use
- medical illness
- limited social supports
etiology
- combination or interaction of:
- genetics (increased risk if first degree relatives suffer from depression, NTs)
- environment
- individual life history
- development
- neurobiological
irregularities in the thyroid are seen especially important - unknown
what NTs are involved
- deficiency in biogenic amines
- dopamine
- norepinephrine
- serotonin
regions of the brain affected by depression
- the brain of a depressed individual is generally underactive, certain areas display overactivity
- thalamus, amygdala, cingulate gyrus, prefrontal cortex
what happens in the thalamus region
- changes in emotion
- increased levels of activity in depressed individuals
what happens in the amygdala region
- responsible for negative feelings
- displays overactivity in depressed people
what happens in the cingulate gyrus
- overactivity
- area helps to associate smells and signs with pleasant memories of past emotions
- it also takes part in the emotional regulation to pain and the regulation of aggression
what happens in the prefrontal cortex
- people who are depressed have DECREASED activity in this section
- help regulate emotion
major depressive disorder parts
- potential for pain and suffering in all aspects of life
- affects children, teens, adults and elderly
- depressed mood or inability to feel pleasure from previously enjoyed activities
- many symptoms
- lasts over a min 2 weeks
symptoms associated with major depressive disorder (4/7)
four out of the seven symptoms must be present:
suicidal ideations, disruptions in sleep, disruptions in appetite/weight, disruption in concentration, disruption in energy level, psychomotor agitation/retardation, or excessive guilt/feelings of worthlessness
- may include psychotic, catatonic, melancholic features
- OVER A MINIMUM 2 WEEKS
persistent depressive disorder
- dysthymia
- chronic depressed mood
> 1 year for children and adolescents
> 2 years for adults and elderly
symptoms of persistent depressive disorder
- poor appetite/overeating
- insomnia/excessive sleep
- low energy
- fatigue
- low self esteem
- poor concentration
- difficulties making decisions
- feelings of hopelessness