Mood Disorders Flashcards
Depression
- pervasive and persistent
- impairs functioning
- may occur in the absence of precipitating events
- may be out of proportion to circumstances
- ‘feel strange’ (difficult to describes)
DSM Major Depressive Disorder criteria
5 or more symptoms in same 2 week period:
- depressed mood
- diminished interest or pleasure in activities
- weight loss/gain or increased/decreased appetite
- insomnia or hypersomnia
- psychomotor agitation or retardation
- fatigue
- feelings of worthlessness or guilt
- difficulty to concentrate
- recurrent thoughts of death or suicidal agitation
Dysthymia
persistent depressive disorder: -depressed mood for most of the day for most days for at least 2 years 2 or more symptoms: -poor appetite or overeating -insomnia/hypersomnia -low energy or fatigue -low self esteem -poor concentration -feelings of hopelessness never been without symptoms for more than 2 months
Manic Episode
- a period of abnormally and persistently elevated or irritable mood and increased goal-directed energy
- lasting at least 1 week
- impairment or hospitalisation
Manic Episode Symptoms
3 or more of the following symptoms:
- inflated self-esteem or grandiosity
- decreased need for sleep
- more talkative than usual or pressure to keep talking
- racing thoughts
- distractibility
- increased goal-directed activity or psychomotor agitation
- excessive involvement in activities that have a high potential for painful consequences
Hypomanic Episode
- 3 or more symptoms of a manic episode
- BUT last for 4 days
- not severe enough to cause a marked impairment in functioning or to hospitalise
Bipolar 1 Disorder
- at least 1 manic episode
- MAY be followed by 1 major depressive or hypomanic episodes
- marked impairment in functioning or need to hospitalise if there are psychotic features
- not due to another medical condition
Bipolar 2 Disorder
- hypomanic episode AND a major depressive episode
- never had manic episode
- not severe enough to cause impairment in functioning or to hospitalise
- not due to another substance or another medical condition
Cyclothymic Disorder
- at least 2 years (1 for children/adolescents)
- hypomanic symptoms that do not meet criteria for hypomanic episode
- periods with depressive symptoms that do not meet criteria for major depressive episode.
- not without symptoms for 2 months
- never meet criteria for mania, hypomania or major depressive episode
- symptoms cause significant distress or impairment
Neurochemical factors of Bipolar Disorder
-abnormalities in levels of dopamine and noreponephrine
serotonin (bipolar)
- regulation of mood
- appetite and sleep
- learning and memory
dopamine (bipolar)
- motivation
- reward and pleasure
norepinephrine (bipolar)
- secreted in response to stress
- lower levels of arousal, alertness and concentration
Prefrontal cortex in bipolar
- lower levels of activation
- representations of goals
- failure to anticipate incentives
Hippocampus in bipolar
- deficits in hippocampus
- dissociates affective response from context
- sadness occurs independent of context
Amygdala in (bipolar)
- increased activation
- attention to stimuli
- priorities threatening info
- interprets it negatively
Anterior cingulate cortex
- regulating emotions when failing to achieve a desired outcome
- deficit in ‘will-to-change’
Hypothalamic Pituitary Adrenocortical (HPA) netwok
- manages and reacts to stress
- triggers secretion of cortisol in response to stress
- cortisol lowers frequency of serotonin transmitters
Psychodynamic theories of (bipolar)
depression is anger turning inward in response to the loss of a significant person
- regress to oral stage:
- integrate person’s identity with your own
- depend on others for support - introjection:
- direct feelings toward the other person onto yourself (anger, guilt)
- self-hatred, low self-esteem, depression
Behavioural Theories (bipolar)
- lack of motivation
- diminished repertoire of behaviours
- less positive social behaviour
- the future lacks positive, fulfilling experiences
Behaviour Theories (bipolar) 3 steps
- lack of appropriate reinforcement
- loss of an important source of reinforcement
- eliciting negative reactions from others
Beck’s Cognitive Theory
- depression is caused by biases in thinking and info processing
- negative schema
- stressful experiences reactivate negative schema
- leads to negative cognitive biases
Negative schema
personality characteristics resulting from adverse childhood experiences (loss)
cognitive distortion:
over generalisation
Unjustified generalisation on the basis of a single event