Mood disorders Flashcards
screening questions depression
last month: feeling down, depressed, hopeless // last month: feeling little interest or pleasure
nice criteria to grade depression
DSM-IV = depressed mood most of day, nearly every day // little interest or pleasure in activities // weight loss or weight gain // insomnia (early waking) or hypersomnia // psychomotor agitation or retardation // loss of energy // feelings of worthlessness or guilt // loss of concentration + indecisive // recurrent thoughts of death or suicide
how many criteria need to be present for depression diagnosis
5
hospital assessment of depression
hospital anxiety and depression (HAD) // patient health questionnaire (PHQ9)
what PHQ-9 score indicated less vs more severe depression
PHQ9 < 16 // PHQ9 >16
what is dythymia
subclinical depression
CT depression
low hippocampal
CSF depression
low monoamine eg serotonin, Na, dopamine
when would antidepressants be recommended in less severe depression
not routinely offered - only if person’s preference // trial psychological first, move to SSRI after 2 weeks
1st treatment option less severe depression
guided self help
order treatment options less severe depression
guided self help // group CBT // group behavioural activation // solo CBT // sola BA // group exercise + mindfulness // interpersonal psychotherapy // SSRI // counselling // STPP
1st treatment severe depression
group CBT + SSRI
examples first line SSRIs in depression
citalopram, fluoxetine, sertraline
if first SSRI not working what is next steps
change to another SSRI –> switch to TCA, MAOi, SNRI
guidance when Switching from citalopram, escitalopram, sertraline, or paroxetine to another SSR
withdraw first SSRI before starting alternative