Mood and Bipolar DOs Lecture Flashcards
Mixed Mania
Rapid Cycling
Bipolar II
Secondary Mania
Subtypes of bipolar DO
Simultaneous mania and depression
>40% prevalence of episodes
what subtype of bipolar?
Mixed mania
>4 episodes a year, what subtype of bipolar?
Rapid cycling
Hypomania (<4 days duration) alternating with depression
..what subtype of bipolar?
Bipolar II
Caused by drugs, tumor, CVA, SLE, endocrine, infections, huntington’s, wilson’s
what subtype of bipolar
Secondary mania
Genetic!
Risk of illness in a first degree relative is 10x the gen pop risk
Bipolar
Decreased inferior prefrontal cortex gray volumes
Decreased cerebellar vermis
Increased amygdala volume
Increased ventricular volume
Structural brain changes seen in bipolar DO
True or False:
The average patient with bipolar disorder does not receive a proper diagnosis for nearly a decade after the onset of his or her first episode
True
True or False…
Pts with cardiovascular disease are more likely to be depressed
true
Depression rates are highest in what type of women?
Early or late perimenopausal
Those using hormone therapy
Anxiety.
Sleep.
Sexual behavior.
Rhythms (Suprachiasmatic nucleus).
Temperature regulation.
CSF production.
which NT?
Serotonin
Mood
Cognition
Motor function
Drive
Aggression
Motivation
what NT?
Dopamine
Mood: – higher functions performed by the cortex.
Cognitive function: – function of cortex.
Drive and motivation: – function of brainstem
Memory and emotion: – function of the hippocampus and amygdala.
Endocrine response: – function of hypothalamus.
what NT?
Norepinepherine
Major Depression w/ or w/o psychotic features
Bipolar disorder - manic or depressed phase
Acute or Catatonic Schizophrenia
Some studies have shown efficacy in treating OCD, Delirium, NMS, Chronic pain syndromes, and intractable seizure disorders
..all indications for what type of therapy?
Electroconvulsive therapy
Relative Contraindications:
Recent MI,
Berry Aneurysm,
Brain Mass,
Increased Intracranial Pressure
Electroconvulsive therapy (ECT)