Mood and Affective Disorders Flashcards

1
Q

What are the risk factors for depression?

A
Bio:
- Low monoamines
- Being female
- Chronic health problem
Psycho
- Personality type
- Poor coping strategies
- Mental health co-morbidities
Social:
- Poor support network
- Stressful events
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2
Q

What is beck’s triad for depression?

A

Negative views about the world
Negative views about oneself
Negative views about the future

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3
Q

What are the core symptoms of depression?

A

Low mood
Lack of energy
Anhedonia - no pleasure in normally pleasurable activities

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4
Q

What are the other symptoms of depression?

A
Cognitive:
- Suicidal ideation
- Guilt/worthlessness 
- Lack of concentration
Biological:
- Diurnal mood variation
- Loss of appetite
- Early morning wakening
- Loss of libido
- Psychomotor retardation
Psychotic
- 2nd person auditory hallucinations
- Persecutory, nihilistic, guilt, hypochondriacal delusions
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5
Q

How long must symptoms be present for before considering a diagnosis of depression?

A

> 2 weeks

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6
Q

What are the DSM-IV (NICE guidelines) stages of depression?

A

Subthreshold: <5 symptoms
Mild: 5 symptoms with minimal functional impairment
Moderate: Somewhere between mild and severe
Severe: Most symptoms with significant impairment

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7
Q

What differentials would you consider for depression?

A

Functional - bipolar, schizophrenia, seasonal affective disorder

Organic - drug use, dementia, hypothyroidism

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8
Q

How is subthreshold and mild depression managed?

A

Watchful waiting with monitoring and sleep hygiene advice

Low intensity therapy: Self help, computerised CBT, group physical activity class

Group based CBT

Antidepressants if:

  • > 2 years
  • Past episode of severe
  • Physical health complications
  • Failure of other interventions
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9
Q

How is moderate-severe depression managed?

A

Suicide risk assessment

SSRI

High intensity therapy: CBT, IPT, behavioural activation

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10
Q

When is ECT used in depression?

A

Life threatening
Psychotic
Severe psychomotor retardation
Failure of other therapies

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11
Q

What is dysthymia?

A

Depressive state for >2 years which doesn’t meet depression criteria

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12
Q

What is cyclothymia?

A

Mood fluctuations for >2 years where elation and depression do not meet criteria

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13
Q

What is atypical depression?

A

Mild-moderate depression with reversal of biological symptoms: e.g. overeating, hypersomnia

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14
Q

What is masked depression?

A

Mood isn’t the prominent feature however sleep disorders and diurnal mood variation are present?

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15
Q

What is seasonal affective disorder? How is it managed?

A

Depressive episodes occurring in the winter months

Treated same as mild depression but don’t give sleeping tablets as makes it worse

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16
Q

What is bipolar affective disorder?

A

Chronic episodic mood disorder characterised by at least 1 episode of mania/hypomania and a further episode of mania or depression

17
Q

What differentials would you consider for bipolar disorder?

A
Thyroid problems
Space occupying lesion
Substance misuse
Schizophrenia
Personality disorders
18
Q

What is the difference between bipolar 1 and 2?

A

1 - mania to depression

2 - hypomania to severe depression

19
Q

What symptoms are associated with bipolar disorder (mania episodes)?

A
More energy
Increased appetite
Grandiose delusions
Increased libido
Little insight
Flight of ideas
Little sleep
Irritable
Easily distracted
Disinhibited
20
Q

What is the difference between hypomania and mania?

A

Hypomania:

  • symptoms >4 days
  • milder symptoms
  • slightly interfere with life
  • partial insight

Mania:

  • symptoms >1 week
  • Greater extent of symptoms - completely disrupt life
  • no insight
  • psychotic symptoms (grandiose delusions or auditory hallucinations)
21
Q

Outline the management strategy for bipolar affective disorder

A
Antipsychotic (olanzapine/haloperidol)
Mood stabiliser (1. lithium 2. valproate)
CBT

(Stop anti-depressants during manic episode but if one is needed for depression prescribe fluoxetine)

22
Q

How is depression screened?

A

Quick check on mood/anhedonia in hx - if yes then more detailed screen

HAD scale and PHQ-9

23
Q

What are some side effects to ECT?

A

Short term - headache, nausea, memory loss, arrhythmia

Long term - some pt. report impaired memory