Montelukast Sodium Flashcards
What doses are available in Singulair?
4mg (chewable), 5mg (chewable), 10mg, 4mg granules (foil packet)
What is the brand name for montelukast sodium?
Singulair
What is the FDA approved indication for Singulair?
for the prophylaxis & chronic treatment of asthma in adults & children 2 years of age & older.
What is the FDA approved dosage for montelukast sodium for adolescents & adults (15+)
one 10mg tablet taken in the evening
What is the FDA approved pediatric dosage for Singulair?
Ages 6-14 (TK 1 T PO 5mg in the evening) & for ages 2-5 the dosage is TK 1 4mg T PO in the evening
What are the other two FDA approved indications for Singulair?
(For the relief of symptoms of seasonal allergic rhinitis for adults & children 2 years+ & perennial allergic rhinitis in adults and children 6 months of age+) and (For the prevention of exercise-induced bronchoconstriction in patients 15+
What is the FDA approved dose for Montelukast when being used for the relief of seasonal or perennial allergic rhinitis?
10mg/day (15+), 5mg/day (6-14), 4mg/day (6m-5)
What is the FDA approved dose for Montelukast when being used for the prevention of exercise-induced bronchoconstriction?
10mg/day, 2 h prior to exercise (15+) Wait 24 hours before taking another dose
What are the possible drug interactions for Singulair?
Phenobarbital may increase the metabolism of montelukast. May also decrease the metabolism of paclitxel, rosiglitazone, repaglinide.
What are the contraindications for Singulair?
Montelukast is not indicated for reversal of bronchospasm in acute asthmatic attacks, including status asthmaticus. Do not replace oral or inhaled steroids with montelukast w/o tapering steroid dose. Singulair inhalation should not be used as mono therapy for exercise-induced asthma. Rare cases of systemic eosinophilia have been documented during therapy after the reduction or stopping of oral corticosteroids. Use with caution in nursing mothers. Pregnancy Category B
What should the RPh consult the patient on for Singulair?
This med should be taken regularly, even when the patient is asymptomatic. This is not intended to treat asthmatic attacks and patients should have appropriate measures at hand to treat attacks. Chewable tablets contain phenylalanine. If a dose is missed, take ASAP. Granules can be given PO or mixed with a spoonful of soft food.
What are the adverse effects of montelukast sodium?
headache, influenza, cough, abdominal pain, dyspepsia, and dizziness. Rare cases include psychiatric disorders (agitation, aggressive behavior, abnormal dreams, depression, & suicidality).
