montelukast ( leukotriene modifiers) Flashcards

1
Q

what is the pharmacological class of montelukast

A

leukotriene modifier

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2
Q

pharmacological action of montelukast

A

suppress effects of leukotrienes
reducing inflammation; bronchoconstriction; airway edema; and mucus production

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3
Q

therapeutic use of montelukast

A

long term therapy of asthma in adults and children; prevent exercise-induced bronchospasm

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4
Q

montelukast is used in children as young as

A

as young as 12 months of age

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5
Q

route of administration of montelukast

A

oral

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6
Q

complications of montelukast

A

depression; suicidal ideation
liver injury

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7
Q

depression and suicidal ideation is more common with which medication

A

montelukast

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8
Q

nursing action because montelukast can cause depression and suicidal ideation

A

monitor changes in behavior and report to provider

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9
Q

nursing action because montelukast can cause liver injury

A

obtain baseline liver function tests and monitor periodically

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10
Q

signs for client to monitor for because montelukast can cause liver injury

A

monitor for indication of liver damage– nausea; anorexia; abdominal pain
notify the provider if manifestations occur

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11
Q

contraindications/ precautions for montelukast

A

safety not established for use in lactating patients
use cautiously in patients who have liver dysfunction

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12
Q

interactions of montelukast with other drugs such as

A

phenytoin

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13
Q

why shouldn’t montelukast be used concurrently with phenytoin

A

can inhibit effects of montelukast

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14
Q

what is the frequency and dose of montelukast should be administered

A

once daily at bedtime

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15
Q

for exercise-induced bronchospasm when should montelukast be taken

A

2hrs before exercise

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16
Q

if a client is taking daily montelukast do they need to take an additional dose for exercise-induced bronchospasm

A

no

17
Q

how is the effectiveness of montelukast evaluated

A

long-term control of asthma