montelukast ( leukotriene modifiers) Flashcards
what is the pharmacological class of montelukast
leukotriene modifier
pharmacological action of montelukast
suppress effects of leukotrienes
reducing inflammation; bronchoconstriction; airway edema; and mucus production
therapeutic use of montelukast
long term therapy of asthma in adults and children; prevent exercise-induced bronchospasm
montelukast is used in children as young as
as young as 12 months of age
route of administration of montelukast
oral
complications of montelukast
depression; suicidal ideation
liver injury
depression and suicidal ideation is more common with which medication
montelukast
nursing action because montelukast can cause depression and suicidal ideation
monitor changes in behavior and report to provider
nursing action because montelukast can cause liver injury
obtain baseline liver function tests and monitor periodically
signs for client to monitor for because montelukast can cause liver injury
monitor for indication of liver damage– nausea; anorexia; abdominal pain
notify the provider if manifestations occur
contraindications/ precautions for montelukast
safety not established for use in lactating patients
use cautiously in patients who have liver dysfunction
interactions of montelukast with other drugs such as
phenytoin
why shouldn’t montelukast be used concurrently with phenytoin
can inhibit effects of montelukast
what is the frequency and dose of montelukast should be administered
once daily at bedtime
for exercise-induced bronchospasm when should montelukast be taken
2hrs before exercise