cetirizine ( antihistamine)- zyrtec Flashcards

1
Q

pharmacological class of cetirizine

A

antihistamine

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2
Q

what generation is cetirizine in

A

2nd generation H1 antagonist

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3
Q

pharmacological action of cetirizine

A

action is on H1 receptor; results in blocking histamine release in the small blood vessels; capillaries and nerves during allergic reaction

relieve itching; sneezing; rhinorrhea;

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4
Q

therapeutic use of cetirizine

A

mild allergic reactions (seasonal allergic rhinitis; urticaria mild transfusion reaction

anaphylaxis ( hypotension; acute laryngeal edema; bronchospasm

motion sickness; insomnia; often used in combination with sympathomimetics to provide nasal decongestant effect

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5
Q

complications of cetirizine

A

sedation; anticholinergic effects; GI discomfort; acute toxicity—-excitation; seizures in children

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6
Q

contraindications of cetirizine

A

use cautiously in children and older adults — respiratory depression

use in clients who have asthma, seizure disorder, cardiac disease, renal disease, urinary retention; open-angle glaucoma hypertension and prostate hypertrophy

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7
Q

interactions with cetirizine

A

CNS depressants; alcohol cause additive CNS depression

avoid alcohol and medications causing CNS depression (opioids barbiturates and benzodiazepines)

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8
Q

effectiveness of cetirizine evaluation

A

improvement of allergic reaction (absence of rhinitis; urticaria
relief of motion sickness decreased nausea and vomiting

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