Monocytes and Dendritic cells Flashcards
Monocytes found in blood, alveoli, and the intestines are called what?
Macrophages
Monocytes found in Connective Tissue are called what?
Histiocytes
Monocytes found in the liver are called what?
Kupffer Cells
Monocytes found in the kidney are called???
Mesangial cells
Monocytes found in the brain are called what?
Microglia
Monocytes found in the bone are called what?
Osteoclasts
This type of dendritic cell is found in the epidermal layers of the skin (cutaneous associated lymphoid tissue, CALT)
Langerhans cells
Excess proliferation of dendritic cells that are found in the epidermal layers of the skin. Not good at being an APC, and express an S-100 tumor marker, and CD1a. On microscopy, will show Burbeck granules.
Langerhans Cell Histiocytosis
Monocytes found in the joints are called what?
A cells
What interleukin activates monocytes?
IFN-gamma
Difference between mast cells and basophils?
Basophils are found in the blood, and mast cells are found in tissue.
What cytokines are produced by macrophages?
IL-1 IL-6 TNF-alpha IL-8, C5a, Leukotriene B4 IL-12 (activates NK cells)