Monoarthritis/gout Flashcards
1
Q
which type of crystals are found in gout
A
urate
2
Q
what contributes to hyperuraemia
A
OVERPRODUCTION
- purine rich diet
- increased synthesis
UNDERSECRETION
- renal impairment
3
Q
which enzyme do humans lack which therefore prevents us breaking down urate
A
urate oxidase
4
Q
3 DDx for a monoarthritis
A
septic arthritis
crystal disease
trauma
5
Q
what is used for the prophylaxis of gout
A
allopurinol
febuxostat
banbromarone
sulphinpyrazone
6
Q
what are the treatments for acute gout
A
NSAIDs
Colchine
Steroids
7
Q
peak incidence for gout
A
men aged 30-60
8
Q
most common pathogen in septic arthritis
A
staph aureus
9
Q
what are the joint depositions in gout called
A
tophi
10
Q
name 5 risk factors for gout
A
male dietary (yeast) kidney problems metabolic syndrome OA
11
Q
list some xanthine oxidase inhibitors
A
allopurinal
febuxostat
12
Q
what process creates urate
A
the breakdown of purines from cell break down
