Monday, 4-11-Vision Physiology (Karius) Flashcards
Accomodation requires:
- Ciliary m.
- Suspensory l.
- Lens itself
Describe the process of near vision regarding ciliary muscle, suspensory ligament and the shape of the lens:
Ciliary muscle contracts –> suspensory ligament tension decreased –> lens becomes rounder –> increased curvature of lens increases refractive power of the lens
Describe the process of far vision regarding the ciliary muscles, suspensory ligaments, and the shape of the lens:
Ciliary muscle relaxes –> tension on suspensory ligament increases –> lens pulled FLAT –> decreased curvature of lens decreases refractory power
The NEAR VISION response requires:
- Contraction of ciliary muscles
- Convergence of eyes to the point of focus
- Constriction of the pupil –> constricting pupil reduces opening for light to enter, eliminates some of diverging light rays, allows to focus better
These cell types have a direct pathway to the optic nerve to the brain:
- photoreceptors (rods and cones)
- bipolar cells
- ganglion cells
Horizontal and amacrine cells do their processing in the retina to increase signal fidelity
The VERTICAL PATHWAY of the retina is composed of these cells:
- Photoreceptor (rod or cone)
- Bipolar cell
- Ganglion cell
Regarding the VERTICAL PATHWAY of the retina, the photoreceptors have a constant release of glutamate. When it is dark (no stimulation), the release of glutamate is __. When a photon activates the photoreceptor, the release of glutamate __
High
Decreases
Regarding the vertical pathway for cones:
- Step 1: A photoreceptor is struck by a photon of light
- Step 2: decrease NT release onto a __ cell and the NT is __
- BIPOLAR
- GLUTAMATE
Regarding the ON-center bipolar cells:
Activation of a photoreceptor in the center of the bipolar cell’s receptive field causes __ of the bipolar cell
Activation of a photoreceptor in the surrounding region causes ___ of the bipolar cell
Depolarization
Hyperpolarization
Regarding the OFF-center bipolar cells:
Activation of a photoreceptor in the center of the bipolar cell’s receptive field causes ___ of the bipolar cell
Activation of a photoreceptor in the surrounding region causes __ of the bipolar cell
Hyperpolarization
Depolarization
Regarding the VERTICAL PATHWAY for cones:
If the photoreceptor activates an ON-center bipolar cell, a __ receptor is activated and NT release causes a __ in cation influx
Metabotropic
Decrease
-Activation of the photoreceptor decreases NT release; So in the dark, the ON-center cell is hyperpolarized and with light, release of Glu from the photoreceptor decreases so the cation current increases and the ON-center cell is depolarized
Regarding the VERTICAL PATHWAY for cones:
If the photoreceptor activates an OFF-center bipolar cell, an __ receptor is activated and NT release causes a __ in cation influx
AMPA
Increase
-Activation of the photoreceptor DECREASES NT release; so in the dark, the OFF-center cell is depolarized and with light, Glu release from the photoreceptor decreases, the AMPA receptor is not activated and the OFF-center cell is hyperpolarized
___ cells are ON-center or OFF-center cells (whatever the connecting bipolar cell is)
Ganglion
In the VERTICAL PATHWAY for cones, the bipolar cell releases __ to excite the ganglion cell. The ganglion cell axons become the fibers for the __.
Glutamate
Optic n.
In the VERTICAL PATHWAY for RODS, many rods converge on 1 ON-center bipolar cell –> synapse on an __ cell –> which synapses on a CONE ON-center bipolar cell –> which activates a ganglion cell
A11 amacrine cell