Monaco Group Activity Flashcards

1
Q

Rh antigens do not activate complement but instead have red blood cells destroyed by oposonization and phagocytosis by macrophages

A

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2
Q

SLE pts do NOT have a monoclonal spike but they do have ab against histones, nuclear proteins, ANA, and ab against dsDNA, and reduced C3 during periods of disease activity

A

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3
Q

leukotriene = late phase molecule

A

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4
Q

what is responsible for wheal part of wheal and flare?

A

histamine

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5
Q

what is HAE?

A

C1 esterase inhibitor deficiency

they have bronchial constriction that can resemble anaphylactic rxns!!

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6
Q

Tb positive test shows…

A

macrophages activated by IFN-gamma

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7
Q

serum sickness is a Type III hypersensitivity rxn

A

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8
Q

type III serum sickness has what mediators?

A

C5a and neutrophils

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