molecular mimicry and autoinflammatory disorders

Question 1

streptococcus pyogens

Answer 1

gram positive pathogen responsible for a large number of varied disease process many of which are immune mediated

Question 2

clinical syndromes dealing with streptococcus pyogens

Answer 2

1. suppurative
2. toxin associated
3. non-suppurative immune mediated
4. scarlet fever
5. streptococcal toxic shock syndrome

Question 3

non-suppurative immune mediated complications of GABHS

Answer 3

acute rheumatic fever

Question 4

acute rheumatic fever

Answer 4

• 6 -15 years
• world wide
• 2-3 weeks after GABNHS pharyngitis

Question 5

diagnosis of acute rheumatic fever uses ____ criteria

Answer 5

jones

Question 6

jones criteria

Answer 6

major:
arthritis 
carditis 
sydenham chorea 
erythema marginatum 
subcutaneous nodules 

minor:
clinical: arthralgia and fever