Molecular: Ferguson Flashcards

1
Q

T/F: Inheritance patterns are based on changes in the genetic sequence.

A

False, based on changes in the packaging, not the genetic sequence

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2
Q

What does a Code Reader Complex do?

A

Reads the histone code

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3
Q

T/F: Histone code is unchangeable.

A

False, changes as the cell needs

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4
Q

Why is having more copies of a gene better?

A

Less need for few mutations

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5
Q

What is the term for a duplicated gene that has been irreversibly inactivated by multiple mutations.

A

Pseudogene

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6
Q

What are the 4 major proteins at a replication fork?

A

DNA polymeraseDNA primaseDNA helicasessDNA binding protein

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7
Q

What does DNA helicase do?

A

Unwinds parent strand of DNA

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8
Q

What does DNA polymerase do and what are its two components?

A

Synthesizes the new DNA strand.Loading clamp and sliding clamp

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9
Q

What does DNA primase do?

A

Creates starting points for DNA synthesis from parent strand

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10
Q

What does ssDNA binding protein do?

A

Binds to ssDNA to prevent parent strands from joining back together

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11
Q

What are the 3 DNA repair pathways?

A

Base excisionNucleotide excisionHomologous recombination

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12
Q

What type of junctions does homologous recombination create?

A

Holliday junctions

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13
Q

T/F: Gene conversion is the more common form of homologous recombination than crossing over.

A

True

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14
Q

When do homologous and sister chromatids separate during meiosis?

A

Homologous: Meiosis ISister: Meiosis II

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15
Q

What can produce genetic variation by inducing spontaneous mutations and can insert anywhere in the genome?

A

Transposons

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16
Q

What are the requirements to be considered a chromosome?

A

Origin of replicationCentromereTelomere