Molecular building blocks Flashcards
formation of macromolecules
simple molecules e.g. sugars, lipids and amino acids can form complex, large molecules
structures and functions of macromolecules
osmotic, structural, optical, enzymatic and other complex functions
v heterogenous
examples of macromolecules
haemoglobin DNA glycogen rhodopsin collagen
what is a chiral centre?
carbon with 4 different chemical groups
D and L monosaccharides
2 optically active and different forms
most sugars in living organisms are D
how are cyclized structures formed?
reaction of aldehyde or ketone groups with a hydroxyl group of the same molecule
sugar derivatives
aminosugars
alcohol sugars
phosphorylated
sulfated
aminosugars
containing amino (NH2) group. often acetylated, e.g. glucosamine
alcohol sugars
sorbitol
phosphorylated
containing phosphate groups
sulfated
sulfate groups, e.g. heparin, chondroitin sulphate
how are glycosidic bonds formed?
hydroxyl group of a monosaccharide can react with an OH or NH group to form glycosides
types of glycosidic bonds
O-glycosidic bonds form disaccharides, oligosaccharides and polysaccharides
N-glycosidic bonds found in nucleotides and DNA
disaccharides
contain 2 monosaccharides joined by an O glycosidic bond
oligosaccharides
3-12 MS
products of digestion of polysaccharides, or part of complex protein/lipids