Molecular Biology of Cancer Flashcards
What is cancer?
NOT a single disease, but rather a group of diseases characterized by uncontrolled growth
What is the root of cancer cell development?
Genetic mutation
Carcinomas Sarcomas Leukemias Lymphoma/Myeloma CNS cancer
Which begin in connective tissue such as bone?
Sarcomas
Carcinomas Sarcomas Leukemias Lymphoma/Myeloma CNS cancer
Which begin in the bone marrow?
Leukemias
Carcinomas Sarcomas Leukemias Lymphoma/Myeloma CNS cancer
Which begin in the brain/spinal cord + most common originating in glial cells?
CNS cancers
Carcinomas Sarcomas Leukemias Lymphoma/Myeloma CNS cancer
Which begin in the lymph glands?
Lymphomas/Myelomas
Carcinomas Sarcomas Leukemias Lymphoma/Myeloma CNS cancer
Which begin in the epithelial tissue such as skin?
Carcinomas
Carcinomas Sarcomas Leukemias Lymphoma/Myeloma CNS cancer
Which is the most common type of cancer?
Carcinomas
Normal vs Cancer Cells
Do not mature into functional cells
Cancer
Normal vs Cancer Cells
Controlled cell division
Normal
Normal vs Cancer Cells
Mortal (die after 50 divisions)
Normal
Normal vs Cancer Cells
Control of angiogenesis
Normal
Normal vs Cancer Cells
Unresponsive to apoptosis
Cancer
Normal vs Cancer Cells
Contact inhibition
Normal
Normal vs Cancer Cells
Increased rate of division
Cancer