Intro & History of Genetics Flashcards
Seeks to use genetic info as well as other molecular assays to facilitate treatment/drug selection, guide drug dosage, and enhance prognostics/diagnostics
- Personalized medicine
- Idiosyncratic drug response
- Pharmacogenetics
- Pharmacogenomics
Personalized medicine
Drug response that is unanticipated for the type of drug and its typical use and outcome
- Personalized medicine
- Idiosyncratic drug response
- Pharmacogenetics
- Pharmacogenomics
Idiosyncratic drug response
Study of genetic variation that gives rise to specific and idiosyncratic drug responses
- Personalized medicine
- Idiosyncratic drug response
- Pharmacogenetics
- Pharmacogenomics
Pharmacogenetics
Broader application of pharmacogenetics to the entire genome. This field is hoped to better facilitate personalized medicine
- Personalized medicine
- Idiosyncratic drug response
- Pharmacogenetics
- Pharmacogenomics
Pharmacogenomics
Gave us the idea of genes; discrete units that are inherited in pairs
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Mendel
Strengthened physical evidence for the nature and behavior of genetic material
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Meischer/Flemmings
Brought Mendel’s important findings back into discussion
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Correns/Tschermak/de Vries
Provided a model for investigating changes in the genetics of populations due to various forces
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Hardy/Weinberg
Chromosomes carry genes
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Morgan
Developed stat. models for population dynamics and evolutionary forces that shape the genetics within and among groups
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Fisher/Wright
Showed that genes code for protein; DNA is more than just passing traits to the next generation
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Beadle/Tatum
Showed that DNA transforms physical properties of cells
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Avery and others
Hinted towards base pairing; critical for development of DNA model
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Chargaff
Used a X-ray crystal photograph that proved the structure of DNA
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Franklin
Developed the first method for sequencing DNA
- Mendel
- Meischer/Flemmings
- Correns/Tschermak/de Vries
- Hardy/Weinberg
- Morgan
- Fisher/Wright
- Beadle/Tatum
- Avery & others
- Chargaff
- Franklin
- Watson/Crick
- Sanger
- Mullis
Sanger