MOLECULAR BIOLOGY Flashcards

1
Q

Action of steptomycin

A
  • Acts only on bacteria

- prevents the transition from translation initiation to chain elongation and also causes miscoding

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2
Q

Action of Erythromycin

A
  • Acts only on bacteria

- Binds in the exit channel of the ribosome and thereby inhibits elongation of the peptide chain

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3
Q

Action of puromycin

A
  • Acts on bacteria and eukaryotes

- causes the premature release of nascent polypeptide chains by its addition to the growing chain end

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4
Q

Action of cycloheximide

A
  • acts only on eukaryotes

- blocks the translocation reaction on ribosomes

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5
Q

Action of tetracycline

A
  • Acts only on bacteria

- Blocks binding of aminoacyl-tRNA to A site on ribosome

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