molecular binding blocks and dna Flashcards
4 different types of proteins
structural
globular
plasma membrane proteins
regulatory proteins
example of structural protein
collagen- formed from 3 polypeptide strands
glycogen
alpha glucose monomer
high level of branching
storage moelcules
structure of cellulose
beta 1, 4 bonds
structure in plants
forms , long parallel chains
structure of starch
amylose- alpha 1, 4
amylopectin- same as glycogen but with less regular branching
Purpose of glycoproteins and glycolipids in cell membrane
For cell signalling
3 types of cell junctions
Tight junctions- prevent diffusion of molecules of adjacent cells
Desmosomes - mechanical atability and tensile strenght
Gap junctions - electrical junctions permitting thr selective transfer of small molecules
Method of endocytosis
Cell membrane fuses around the substance to be moved into the cell
Forms a vacuole
Molecule released into cytoplasm by fusion of membrane
Process of exocytosis
Membrane of vesicle fuses cell surface membrane and releases contents into ECF
Process of primary active transport
Atpase binds to molecule
Atp phosphorylates , this releases energy and induces a conformational change in protein
ions are released into the extracellular space
Atpase reverts to original confirmation
Membrane proteins and their roles
Transporters - transport small molecules sich as ions across the membrane
Anchors- lipid anchored cell membrane , anchor the protein to cell membrane
Receptors- cell signalling by binding to extracellular molecules
Enzymes- such as maltase
Steps in dna replication
Topoisomerase unwinds the supercoil and breaks the phosphodiester bonds
Helicase breaks hydrogen bonds between bases
Dna polymerase reads strands 3 to 5 and synthesises 5 to 3
Leading and lagging strand leaves a gap filled by dna ligase
Transcription and translation
Transcription in nucleus , with topisomerase and rna polymerasw mrna moves out of nuclear pores pre mrna to mrna with splicing
Translation trna carries a specific anti codon to the corresponding codon on mrna
Produces a chain fof amino acids until stop codon is reached
Steps in beta oxidation
Lipase breaks down a triglyceride into fa and glycerol
Free fa enters cyroplasm w fa transporter
With acyl coA synthase fa is converted to acyl coa with the release of amp and pp from atp
Carnitine palymoyl transferase attaches carnitine to acyl coa to make acyl carnitine
Carnitine acylcarnitine translocase acyl coa into matrix of mitochondria
Carnitie palmitoyl transferase 2 acyl carnitine into acyl coa and carnite into the inner mitochondrial matrix.
what is a nucleoside
pentose sugar and base no phosphate