Molecular Basis Of Inheritance

Question 1

Nucleosomes are the repeating units of?

Answer 1

chromatin

Question 2

A typical nucleosome contains ___ bp of dna

Answer 2

200

Question 3

Dna as an acidic substance was identified by

Answer 3

Friedrich meischer in 1869. NUCLEIN

Question 4

How many nucleosome arw present in a mammalian cell?

Answer 4

3.3 * 10^7

Question 5

The packaging of chromatin at higher level requires additional set of proteins that collectively are called

Answer 5

NHC
NON HISTONE CHROMOSOMAL PROTEIN

Question 6

Transforming principle

Answer 6

1928 Fredrick Griffith

Question 7

The unequivocal proof of dna js genetic material was given by

Answer 7

Alfred Hershey and Martha chase in 1952

Worked on bacteriophage

Question 8

For transmission of genetic material

Answer 8

RNA IS BETTER

Question 9

Dna replicates semi conservatively was proven first in

Answer 9

E.coli.. experiment - Matthew Meselson and Franklin Stahl
1958

Question 10

E coli divides in

Answer 10

20 mins

Question 11

The main enzyme for dna replication is

Answer 11

DNA DEPENDENT DNA POLYMERASE

Question 12

E Coli completes replication in

Answer 12

18 mins

Question 13

Who serves dual purpose in replication

Answer 13

Deoxy ribonucleoside triphosphates

Question 14

Can ds rna be translated

Answer 14

Naurrr

Question 15

Wat is the polarity of template strand

Answer 15

3’ to 5’

Question 16

Which sequences do not appear in mature and processed rna

Answer 16

INTRONS

Question 17

Split gene arrangement is seen in ?

Answer 17

Eukaryotes

Question 18

M-rna acts as a template
R-rna is structural and catalytic then wat is the function of t-rna

Answer 18

T- RNA brings amino acids and reads the genetic code

Question 19

STATE TRUE OR FALSE

There is a SINGLE dna dependent rna polymerase that catalyses transcription of all types of rna is bacteria

Answer 19

TRUE

Question 20

In prokaryotes wat is the predominant site for control of gene expression

Answer 20

Control of the rate of transcriptional initiation

Question 21

Lac operon was seen by

Answer 21

Geneticist Francois Jacob and biochemist Jacque Monod

Question 22

Can glucose and galactose act as an inducer for lac operon

Answer 22

Naurr

Question 23

Largest human gene

Answer 23

Dystrophin gene at 2.4 million bases

Question 24

State true or false
Almost all (99.9%) nucleotide bases are exactly the same in all

Answer 24

True

Question 25

Chromosome 1 has most genes ( 2968) then which has the lowest

Answer 25

Y has fewest (231)

Question 26

Wat is dna polymorphism

Answer 26

If an inheritable mutation is observed in a population at high frequency it is referred to as DNA polymorphism

Question 27

Vntr belongs to

Answer 27

Mini satellite

Question 28

Size of vntr varies from

Answer 28

0.1 to 20 kbp

Question 29

Thr smallest RNA is

Answer 29

T- RNA

Question 30

If coding strand has sequence CAT the transcribed mrna will have

Answer 30

CAU

Question 31

Reverse transcription is done by?

Answer 31

RNA dependent DNA POLYMERASE

Question 32

Which chromosomes in humans has the most genes

Answer 32

Chromosomes 1

Question 33

In eukaryotes peptidyl transferase which catalyses the synthesis of peptide bond is

Answer 33

28S rRNA

Question 34

During DNA packaging kn eukaryotes histone octamer doesn’t have

Answer 34

H1

Question 35

Darwin’s finches are examples of

Answer 35

Adaptive radiation
Divergent evolution
Geographical isolation
Founders effect

Question 36

A nucleotide lacks

Answer 36

Phosphodiester linkage

Question 37

How many types of HISTONEs form the core part of nucleosome

Answer 37

4

Question 38

Eras period epochs

Answer 38

Yess