Molecular

Question 1

In PORTEC-3, how many of grade 1-2, stage II-III, tumors had p53 mutations?

(only enrolled stages II-III, for g1-2)

Answer 1

2.5% = 4/161

Question 2

In PORTEC-3, how many of stage III cancers had POLE mutation?

Answer 2

III: 7% - 12/178 overall

IIIA: 4% - 2/46

IIIB:14% - 4/29

IIIC: 6%- 6/103