Clinical Pearls Flashcards
1
Q
PORTEC-3 study (s.I g3 EAC w/ deep invasion and/or LVSI, EAC s.II-III, s.I-III UPSC or CCC) XRT vs. Cis XRT followed by CP#4: at median f/u of 5y: OS, PFS and isolated recurrences? Lancet Oncology 2018; 19:295-309
A
No ss difference in OS 5y failure free survival: 7% difference (76 vs. 69%, p=0.022) isolated vaginal or pelvic 🔄: < 1% in each group(/\ XRT) 8 vs 1% grade 2 neuropathy at 3y in Cis XRT group
2
Q
Risk of EAC after endometrial ablation in Finnish 5484 pts (no BMI reported)
A
Equal to baseline: 3 cases reported 20% had postablation TLH, 1.8% of those (20 pts) had hyperplasia as indication
3
Q
5y DSS for UPS vs. g3 EAC per SEER: stages I/II?
A
74 vs. 85%
