Molar Pregnancy (Hydatidiform mole) Flashcards
What is this?
What occurs in a Complete mole?
What occurs in a Partial mole?
➊ Tumour that grows like a pregnancy in the uterus
➋ 1 sperm with an empty egg. This sperm then replicates to give a normal number of chromosomes. No foetal material will form; just a proliferation of swollen chorionic villi.
➌ 2 sperm with a normal egg, so the new cell has 3 sets of chromosomes. Foetal material will form.
How does it present?
How is it diagnosed? What will be seen?
What are its main complications?
How is it managed?
➊ * Hyperemesis gravidarum as b-hCG is very high
* PV bleeding
* Uterus larger than expected for gestational age
* Thyrotoxicosis as b-hCG can mimic TSH
➋ * B-hCG – Really high
* TVUS – Snowstorm appearance
➌ Thyrotoxicosis, Choriocarcinoma (metastatic uterine cancer), Pre-eclampsia
➍ Evacuation of uterus
N.B. After evacuation, the levels of b-hCG are expected to fall and pregnancy should be avoided for 1 year. However, if they fail to drop, you should suspect malignant choriocarcinoma.
