Module D: Psychotherapeutics

Question 1

4 Categories of Antidepressants

Answer 1

1- Tricyclic Antidepressants (TCAs)
2- Selective Serotonin Reuptake Inhibitors (SSRIs)
3- Selective Norepinephrine Reuptake Inhibitors (SNRIs)
4- Monamine Oxidase Inhibitors (MAOs)

Question 2

2 Categories of Antipsychotics/Neuroleptics

Answer 2

1- typical - HALDOL (Haloperidol)

2- atypical - CLOZARIL (Clozapine)

Question 3

Adverse effects of antipsychotics

Answer 3

• motor abnormalities

- muscarinic and a1 adrenergic blockade

Question 4

Advantages of atypical antipsychotics vs typical

Answer 4

• fewer motor abnormalities

- greater effect on symptoms of schizophrenia

Question 5

Mechanism of Action Antipsychotics

Answer 5

• block dopamine and serotonin receptors

- used to Tx major psychoses (ie. schizophrenia)

Question 6

Use of Antidepressants

Answer 6

• affective disorders - depressive and bipolar
• anxiety disorders
• sleep disorders
• chronic pain syndromes

Question 7

Tricyclic Antidepressants (TCAs)

Answer 7

ie. amitriptyline, clomipramine, desipramine,imipramine, nortriptyline
- block neuronal reuptake of Norepi and serotonin
- highly effective in Tx of depression
- associated with high incidence of adverse effects - severe toxicity in excessive doses ie. cardiac arrhythmia, hypotension, excessive sedation, seizures