Module 8: Non-Infectious Disease and Disorder Flashcards
Why is homeostasis important?
To maintain proper functioning of enzymes
What systems are involved in homeostasis?
The hormonal system and nervous system
What are the two main components of the negative feedback loop?
Detecting change or the stimulus
Counteracting the change
What systems coordinate the negative feedback loop?
Nervous system or the endocrine system
What is the hypothalmus?
A part in the brain which is an important control centre
What are the effectors when there is an increased body temp?
Blood vessels, sweat glands, cells
What are the responses to increased body temp?
Blood vessels dilate
Sweat glands secret sweat evaporation leads to heat loss
Metabolic rate of cells decreases
What are effectors when there is a decreased body temp?
Blood vessels
Muscles
Cells
Hair erector cells
What are the responses to decreased body temp?
Blood vessels constrict
Muscles cause shivering
Metabolic rate of cells increase
Erect hair traps air
What are receptors responsible for?
Detecting stimuli
What do thermoreceptors detect?
Change of heat
What do chemoreceptors detect?
Concentration of certain chemicals
What do osmoreceptors detect?
Osmotic pressure
What are the two parts of the nervous system?
The central nervous system
The peripheral nervous system
What is the CNS composed of?
Brain and spinal cord
What is the PNS composed of?
All other nerves in body
How are messages transmitted by the nervous system?
In the form of electrochemical impulses
What is the cell body of a neuron?
Contains the nucleus
What are dendrites in neurons?
Fine branches which conduct nerve pulses towards cell body
What are axons in neurons?
Long extension which conduct messages away from cell body
What are sensory neurons?
Neurons which carry messages from sensory cells
What are motor neurons?
Neurons which transfer messages to muscles or glands
What are interneurons?
The link between sensory and motor neurons
What is the synapse?
A small gap between neurons
What are nerves?
A bundle of neurons gathered together by fibres
How are messages transmitted in nerves?
Electrochemical impulses
What is action potential?
Change in electrical potential during electrochemical impulses
What happens during action potential?
There is a change in concentration of ions on either side of the membrane
When is a neuron at rest?
When no message is being transmitted
What is the resting membrane potential?
-70mV
What is the ion arrangement around neurons when at rest?
Lots of Na+ ions outside and little K+ ions inside
What is the membrane called at rest?
Polarised
What happens when stimulus is detected?
Sodium channels open and Na+ move in to neuron reducing overall negative charge
What is the threshold value?
-55mV
What happens if threshold value is met?
Na+ ions will continue to move in regardless of stimulus
What happens when Na+ moves into the neuron?
Causes inside to be more positive known as depolarisation
What happens during depolarisation?
Potassium channels also open allowing K+ ions to move out known as repolarisation
How long are potassium channels open for?
Slightly longer than sodium channels
What does action potential trigger?
The release of neurontransmitters
What are neurontransmitters and what do they do?
They are chemicals that move across the synapse initiating an action potential
What type of matter is the brain and spinal cord made up of?
White and grey matter
What does grey matter mainly consist of?
Neuron cell bodies
What does white matter mainly consist of?
Nerve fibres
Where is grey matter in the brain?
On the outside
Where is grey matter in the spinal cord?
In the centre
What is the brain?
Main control centre of the body
What does the spinal cord do?
Provides link between the peripheral nervous system and brain and coordinates reflex actions
What does the endocrine system use?
Hormones which are secreted by endocrine glands
How are hormones transported in the body?
Via the blood
What do hormones do?
They influence activity of particular enzymes
What is the pancrease made up of?
Structures called pancreatic islets
What do the pancreatic islets do?
Produce hormones insulin and glucagon
What type of cells are in pancreatic islet cells?
Alpha and beta cells
What do beta cells do?
Detect high levels of glucose and produce insulin
What does insulin do?
Allows glucose to be removed from the blood by forming glycogen
What do alpha cells do?
Detect low levels of glucose and produce glucagon
What does glucagon do?
Stimulates the production of glucose by breaking down glycogen
What are endotherms?
Organisms which can maintain their body temp
What behavioural adaptions do endotherms have to maintain body temp?
They alter or move the position of their body to increase or decrease temp
What are some examples of behavioural adaptions of endotherms to maintain body temp?
Penguins huddle together when cold or go in water when hot
Nocturnal activity prevents exposure to heat of the day
What structural adaptions do endotherms have to maintain body temp?
Insulation like hair, feather, fur and fat prevent heat loss
Surface area such as small or big ears
What physiological adaptions do endotherms have to maintain body temp?
Metabolic activity can be altered
Shivering
Hibernation
Sweating or panting
What is transpiration?
Evaporation of water from the stomata
What are xerophytes?
Plants that live in arid conditions
What are 8 adaptations of xerophytes?
Shiny wax and thick leathery cuticles
White hair on leaves
Orientation of leaves
Reduced surface area
No leaves
Regulating open and close of stomata
Fleshy stems and leaves
Woody fruits
What are non-infectious diseases?
Disease which is not caused by pathogens and are not contagious
How much do non-infectious diseases account for deaths in aus?
Account for the four leading causes of death
What are genetic diseases caused by?
Mutations of the genes or chromosomes or abnormal cell division
What causes single gene abnormalities?
When a person inherits mutated genes from parents
What diseases does single gene abnormalities cause?
Cystic fibrosis, albinism and sickle cell anaemia
What causes cystic fibrosis?
Mutation of the CFTR
How does the mutation of CFTR cause cystic fibrosis?
The faulty gene changes the protein which regulates NaCl movement
What does cystic fibrosis cause and affect?
Causes abnormally thick mucus which affects the respiratory, digestive and reproductive system
What are the two types of chromosomal abnormalities?
Incorrect number of chromosomes and a change to the chromosome
What causes an incorrect number of chromosomes?
Non-disjunction
Trisomy
Monosmy
What is non-disjunction?
Incorrect seperation of chromosomes
What is trisomy?
One extra chromosome with a normal pair
What is monosmy?
When one member of chromosome pair is gone
What happens to babies with monosmy or trisomy?
They will have a syndrome which is a group of symptoms which relate to a disease
What is deletion of a chromosome?
When a chromosome breaks and some of it is deleted
What is translocation?
When a section of a chromosome moves to join another
What is down syndrome?
The most common trisomy syndrome
What causes down syndrome?
An extra chromosome 21
What are the characteristic facial features of down syndrome?
Small flat skull, almond shaped eyes and small ears that fold over
What are the impacts of down sydrome?
Intellectual disability and heart defects
What are lifestyle diseases?
Those that directly arise from the way people live their life
What are the four most common lifestyle diseases?
Cardiovascular disease
Diabetes
Cancers
Chronic lung disease
What are the risk factors of lifestyle diseases?
Tobacco use, unhealthy diet, physical inactivity, harmful use of alcohol
What physical factors can cause disease?
Exposure to UV and radiation