Module 8: Epoxide Ring Opening Reactions Flashcards
1
Q
What ring-opening reactions did we learn?
A
- RONa + H2O
- NaCH + H2O
- NaSH + H2O
- RMgBr + H2O
- LAH + H2O
2
Q
What carbon is attacked in the nucleophilic substitution?
A
Under normal conditions:
* Least substituted (Primary > Secondary > Tertiary)
Acidic conditions
* Tertiary > Primary > Secondary