Module 7: Electrophilic Aromatic Substitution Flashcards
1
Q
What EAS reactions did we cover?
A
- Halogenation
- Sulfonation
- Nitration
- Friedel-Crafts Alkylation
- Friedel-Crafts Acylation
- Alkene Reactions with Acids
2
Q
Halogenation
A
Br2 and FeBr3 or AlBr3 (for adding bromine)
Cl2 and AlCl3 (for adding chlorine)
3
Q
Sulfonation
A
Fuming H2SO4 (SO3 gas)
* Adds SO3H benzene ring
4
Q
Nitration
A
HNO3 and H2SO4
* Adds NO2 to benzene ring
5
Q
Friedel-Crafts Alkylation
A
Alkyl halide and AlCl3
* Rearrangements occur before the addition
* Halide must be on a sp3 carbon
6
Q
Friedel-Crafts Acylation
A
Acyl halide and AlCl3
* No rearrangements (not a sp3 carbon)
7
Q
Alkene Reactions with Acids
A
Alkene or Alcohol with H2SO4 or H3PO4
* Forms carbocation