Module 8 Flashcards

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1
Q

Define homeostasis

A

The process of maintaining a stable internal environment despite changing external conditions

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2
Q

Process of temperature homeostasis

A

Change in external temperature detected by thermo-receptors —> message sent to hypothalamus via nerve —> message sent to effectors to either dilate blood vessels and sweat or constrict blood vessels and shiver.

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3
Q

Process of Glucose homeostasis

A

Change in blood glucose levels detected by pancreatic cells—> liver breaks down glycogen or takes up glucose —> blood glucose rises/declines to a set point and homeostasis is restored.

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4
Q

Process of water homeostasis

A

Water levels change —> hypothalamus detects change —> pituitary glad stops/starts releasing ADH —> ADH stops/starts acting on the kidney by increasing/decreasing the permeability of the nefrons.

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5
Q

What are the behavioural adaptations to maintain homeostasis?

A
  • movement to different environments (shade/sun)
  • deliberate use of muscles (metabolic heat)
  • sunbaking (radiation)
  • licking (evaporation of saliva)
  • drinking water
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6
Q

How does genetic engineering help/fix non infectious diseases

A

Gene therapy: inserting corrected gene sequencing into a cell where a defect has occurred - techniques used to do this include insertion of viral vectors, gene gun and inorganic particles
CRISPR: point mutations to dysfunction cells this alters the genomes resulting in a lasting somatic cell edit
Embryo screening or editing: screening allows implanting embryos without genetic defect editing within embryos allows while organism changes

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7
Q

The ear (sections)

A

The outer ear: pinna (ear lobe ect) and ear canal
The middle ear: ear drum and ossicles (hammer, anvil and stirrup)
The inner ear: cochlea, semicircular canals (balance) and auditory nerve

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8
Q

The pathway of sound through an ear

A

Sound enters the ear in the form of waves the EAR DRUM vibrates this movement causes the the OSSICLES to move in a chain like fashion. This movement knocks on the membrane window of the COCHLEA the cochlea is filled with fluid which moves in response hair cells lining the cochlea are bent in response which creates an electrical impulse to be sent along the AUDITORY NERVE and to the brain

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9
Q

Conductive hearing loss and what can cause it

A

Occurs when there is damage to outer or middle ear resulting in ineffective sound transfer
The cochlea may still be functional but does not recievce sufficient signal to create an auditory impulse
May be a result from infections, abnormal bone growth in middle ear or perforation of the eardrum

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10
Q

Sensorineural hearing loss and what can cause it

A

Occurs when there is damage to inner ear, sound may arrive at cochlea but is not properly passes to auditory nerve or the nerve itself may be damaged
Damage may be congenital as a result of genetic factors or disease or acquired due to factors such as age, noise exposure, physical trauma or diseases such as meningitis

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11
Q

Pathway of light through the eye

A

Light-> cornea -> pupils (can dilate and contract iris to change how much light entered the eye) -> lens (focused light) -> through vitreous gel-> light rays come to a focal point image is focused at the retina-> as light hits the retina light energy is converted into electrical impulses by the rods and cones which sends the messages onto the optic nerve -> brain

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12
Q

What is it called when light does not focus properly in the eye due to incorrect shaping of the cornea

A

Refractive errors

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13
Q

What is myopia and what lens shape assists

A

(Near sightedness) occurs when the cornea is too curved or the eyeball is too long resulting in light refracted at an angle which places the focal point in front of the retina
Concave lenses allow light to focus on retina

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14
Q

What is Hyperopia and what lens assist

A

(Far sightedness) occurs when the cornea is too flat or the eyeball is too short resulting in light being focused beyond the retina ( objects close up are blurry)
Convex lenses allow light to focus properly on retina

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15
Q

Astigmatism, glaucoma and cataracts

A

Astigmatism: disorder where vision is blurred at all distances as a result of misshapen cornea
Glaucoma: blindness due to build up of pressure in the eye causing optic nerve damage
Cataracts: clouded areas in the lens causing blurry or tinted vision

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16
Q

List the causes of genetic diseases

A
  • gene or chromosome abnormalities caused by point or chromosomal mutations ( may result from errors during gamete formation or exposure to mutagens)
  • inherited from parents
  • acquired changes to pre- existing genes
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17
Q

Give an example and the cause of a genetic disease.

A
  • Down syndrome - chromosomal abnormality
  • cystic fibrosis - single gene disorder
18
Q

What are the causes of environmental diseases.

A

-Interaction with the environment
-exposure to physical factors such as radiation
- exposure to harmful or toxic chemicals

19
Q

Give an example and the cause of an environmental disease.

A

-Minamata-ingestion of large amounts of mercury
- Mesothelioma- cancer as a result of asbestos exposure

20
Q

List the causes of nutritional diseases and give an example.

A
  • issues with diet-excess or insufficient consumption of food ( particular foods)
  • problems with digestion
  • consumption of incorrect amounts of specific foods - essential vitamins or minerals

E.g. scurvy, type 2 diabetes

21
Q

List the causes of cancer.

A
  • infectious agents
  • genetic disorders
  • exposure to mutagenic environmental factors
  • lifestyle habits
22
Q

What are some examples of different cancers and their causes.

A

Cervical cancer- from HPV exposure
Breast cancer- genetic inheritance
Melanoma - repeated sun exposure
Lung cancer - from smoking

23
Q

Define cancer.

A

Cancer is a disease in which abnormal cells grow in an uncontrolled manner as a result of changes to the fundamental molecular functions of a cell due to mutation.

24
Q

What are the defining aspects of cancerous cells.

A
  • replicate indefinitely
  • evade growth suppressors in the body
  • resist cell death
  • induce increased blood flow to the tumour site
  • invade other tissues and metastasise
25
Q

What are the kidneys basic function

A

Kidneys are the body’s cleaners processing blood to filter out waste products and balance salt and water levels

26
Q

Structural adaptations to maintain homeostasis

A
  • insulation (feathers, fur ect to reduce heat transfer with environment)
  • SA:V ratio (lower sa:v mean less heat exchange with environment)
27
Q

Kidney process (nephron order)

A

Blood enters the kidney-> glomerulus -> bowman’s capsule (RBCs back to capillary’s) ->proximal convoluted tubule (essential molecules as water, glucose, salts and nutrients are transferred back into capillaries) -> loop of henle -> distal convoluted tubule -> collecting duct -> renal pelvis

28
Q

Physiological adaptations to maintain homeostasis

A
  • vasoconstriction/vasodilation can I regulate SA:V ratio of circulatory system
  • regulating metabolism
  • muscle contraction (shivering)
  • sweating (evaporation of sweat takes heat with it)
  • panting (allows evaporation from internal body surfaces)
29
Q

What are endotherms?

A

Organisms capable of regulating the body to maintain a constant internal temperature (homeostasis).

30
Q

Kidney failure may be a result of:

A
  • diabetes
  • high blood pressure
  • inflammation of important filtration structures
  • obstruction of the kidney (ie kidney stones or tumours)
  • infection (ie uti)
31
Q

How do hormones work?

A

1 - reception: the hormone binds to a cells receptor
2 - transduction: the binding event triggers a signalling cascade within the cytoplasm
3 - response: cell signalling initiates a response (usually to begin polypeptide synthesis)

32
Q

What do hormones do?

A

Hormones are responsible for regulating expression of proteins to dictate cell function. This includes altering the rate of metabolism, digestion, respiration, sleep, growth, reproduction and mood.

33
Q

What are cochlear implants and there basic function?

A

Electronic devices which replace the function of damaged inner ears (cochlear)
It enables sound received through an external transmitter to be transferred to the auditory nerve

34
Q

What does laser surgery do?

A

It is used to reshape the cornea in order to correct vision problems, it reshaped the cornea so that it focuses light more accurately
(Myopia = flatten cornea)
(Hyperopia = increase curve of cornea)

35
Q

What does dialysis do and what are the two main types?

A

Dialysis refers to the removal of metabolic wastes, salt and extra water from the blood by allowing dissolved solutes to pass across a semipermeable membrane
Types
Haemodialysis (performed at hospital) : waste filtered from the blood outside of the body in a dialysis machine
Peritoneal dialysis (can be performed at home by urself) :cleansing fluid is flown into the peritoneal cavity in the abdomen by a catheter

36
Q

When is dialysis needed?

A

Dialysis is used when kidneys have lost their ability to filter waste products from the blood

37
Q

What does epidemiology study ?

A

Epidemiology is the study of incidence, distribution and possible control of diseases. - Describes the patterns and causes of diseases within populations.

38
Q

What components are necessary for an epidemiology study to be valid?

A
  • select population with varying exposure to possible cause as the study must include an independent variable
  • have a large sample size
  • collet data on a range of factors which may affect diseases e.g. age, sex, ethnicity
39
Q

What are the three main types of epidemiological study and what do they consist of ?

A

Descriptive - a study of the patterns of distribution of a diseases within and across populations
Analytical - examination of known associations or testing specific hypotheses
Experimental - measures the effectiveness of interventions, clinical or community trials of treatments

40
Q

Positive VS negative feedback loops

A

Negative - bring the body towards homeostasis
Positive - brings the body further from homeostasis

41
Q

Movement of nerve impulses

A

Stimulus —> receptor —> control centre (brain) —> effector —> response

42
Q

How do plants balance water levels?

A
  • the amount of water is regulated by the transcription-cohesion-tension theory.
  • By regulating transcription by: - reducing SA:V
  • closing stomata
  • dropping leaves
    water can be balanced