Module 7: Renal Physiology Flashcards
site of glomerular filtration
renal corpuscle
site of reabsorption and secretion
bowman’s capsule
establishes the hyperosmotic medullary gradient
loop of henle
bulk reabsorption of solutes and water
proximal tubule
fine-tuning of solute reabsorption/secretion
distal tubule and cortical collecting duct
movement of a substance from the tubule to the peritubular capillaries
basic renal process of tubular reabsorption
movement of a substance from the peritubular capillaries to the tubule
basic renal process of tubule secretion
filtration of plasma from glomerular capillaries into bowman’s space
basic renal process of glomerular filtration
mechanisms of tubular reabsorption
diffusion down concentration gradient
mediated transport
movement into interstitial fluid along concentration gradient
movement from interstitial fluid to blood by bulk flow or diffusion
diffusion down concentration gradient
requires active transport and energy
1 degree transcellular
mediated transport
types of mediated transport
Na/K - ATPase
Na/glucose
Na/AA Co-transport
Na tubular reabsorption is an example of
active transport
maximum amount of material that can be transported per unit time
occurs when binding sites on transport protein are saturated
transport maximum
secondary active transport or water soluble vitamin are examples of
transport maximum
dilation of the efferent arteriole causes DECREASED glomerular filtration rate (GFR) by
decreasing glomerular capillary hydrostatic pressure
substance that is freely filtered, not reabsorbed and not secreted
inulin
substance that is freely filtered, not reabsorbed and not secreted can be used to determine the
following normal renal function value
125mL/min glomerular filtration
mL/min!!!!
substance that is freely filtered and 100% secreted
creatinine
substance that is freely filtered and 100% secreted measures which of the following renal functional
parameters
renal plasma flow
key factor necessary for the generation of hyperosmotic urine by the countercurrent
multiplier system
active transport of sodium in the ascending limb of the loop of henle
renal hormone responsible for the formation of Angiotensin I
renin
steroid hormone made by the adrenal cortex, helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body
aldosterone
controls na+ absorption
aldosterone
ANP at tubules
directly alters aldosterone secretion
angiotensin II
water is reabsorbed in
proximal tubule
descending limb of loop of hence
ureter
water is NOT reabsorbed in
ascending limb of loop of hence
production of hypoosmotic (dilute) urine requires
low vasopressin
results from decreased solute reabsorption, decreased water reabsorption, increased solute excretion
osmotic diuresis
the HCO3- buffering system is highly effective because
the elimination of CO2 in the lungs
is compensated by decreasing HCO3- recovery
respiratory alkalosis
will cause a pH <7.4
hyporventilation
