Module 6 : Liver Vasculature Flashcards
1
Q
hepatic artery
A
- primary blood supplier (30%)
- tortuous
- low resistance
2
Q
proximal HA
A
- best seen in transverse
- at celiac axis
+ is celiac axis occluded then HA can still get flow from collaterals
3
Q
distal HA
A
- viewed intercostally
- ## at level of main portal vein
4
Q
spectral tracing of normal HA
A
- low resistance
- fill in of spectral window due to small artery diameter
- variable viscosities due to tortuosity
- RI 0.5-0.7
5
Q
resistive index RI
A
- EDV/PSV
- EDV decreases = more resistive
- stronger indicator of stenosis then velocity
6
Q
inferior vena cava IVC
A
- formed by union of the common iliac veins
- anterior to the spine and to the right of the aorta
- intercostal scans are best to visualize
7
Q
IVC spectral waveform
A
- spontaneous waveform (no provocative maneuver)
- Proximal = more pulsatile closer to heart
- distally = phasic (further from heart)
- respiratory changes
8
Q
IVC size
A
- changes with size of patient
- respiration
- right atrial pressure CHF
- > 3.7 dilated
9
Q
hepatic veins
A
- three major veins
- accessory veins are common (more on right)
- drain into IVC
- hepatic veins enlarge as they approach the IVC
- intersegmental
- commonly left and middle come together first
- with agenisis RHV usually absent followed by middle then left
10
Q
right hepatic vein RHV
A
- runs coronally between anterior and posterior segments of the right lobe
- largest
11
Q
middle hepatic vein MHV
A
- lies between right and left lobes
- medial left lobe
12
Q
left hepatic vein LHV
A
- runs between the medial and lateral segment of the left lobe
- commonly duplicated
13
Q
caudate lobe
A
- has its own drainage directly into IVC
14
Q
spectral trace hepatic veins
A
- multiphasic
- pulsatile flow
- flow away from transducer
- if not showing this flow there may be an obstruction
15
Q
walls of hepatic veins
A
- less defined then PV
- no echogenic sheath
16
Q
patency and distension hepatic veins
A
- indications of Budd Chiari or CHF
- BC = narrowed or absent
- CHF = not phasic or pulsatile
17
Q
hv scanning window for confluence
A
- trans subxiphoid
- lots of color close to heart
18
Q
hv scanning window RHV
A
- right intercostal
19
Q
hv scanning window MHV
A
- midline subxiphoid
- intercostal
20
Q
hv scanning window LHV
A
- anterior subcostal
- angle heel toward left
21
Q
portal veins
A
- drains nutrient rich blood from bowel and spleen to the liver (70%)
- formed by confluence of the splenic vein and SMV
+ IMV and coronary veins contribute - enters liver at porta hepatic
22
Q
portal veins spectral trace
A
- low velocity \+ range = 15-40 cm/sec \+ mean = 15-18 cm/sec - continuous signal - subtle phasic variations (undulations) - windstorm sound
23
Q
portal veins flow
A
- hepatopedal (toward flow)
- increases post prandially
+ vessels dilate near bowel when you eat which increases flow
24
Q
scanning window MPV
A
- anterior subcostal
- intercostal
- always over ivc
25
scanning window RPV
- intercostal
| - coronal
26
scanning window LPV
- subxipoid
| - intercostal
27
liver duplex exam - assessing
- flow direction
- normal waveform
- patency
28
liver duplex exam - routine vessels
- hepatic veins
- portal vein
- splenic vein
- hepatic artery
- collaterals
29
dopper assessment liver duplex
- assess flow quality
| - only assessed during quiet respiration
30
patient positon
- supine
31
anterior window
```
- assess
+ LPV
+ LHV
+ SV
+ MPV
```
32
coronal intercostal
```
- assess
+ RHV
+ MHV
+ RPV and MPV
+ HA
```
33
color and spectral doppler of liver
- done in every picture
- flow direction
- quality of flow NOT QUANTITY
- patency
34
hepatic veins assess
- hepatofugal (away from liver) flow
| - multiphase waveform
35
portal veins assess
- hepatopedal
| - subtle phasicity
36
MPV - protocal
```
- 2D (anterior subcostal)
+ measure AP
+ anterior to IVC
+ with quiet respiration
+ normal measurement less than 13mm
- color and spectral trace (coronal intercostal)
+ sample MPV outside of liver
+ coronal intercostal
= zero angle
+ anterior subcostal
= 60 angle
+ measure peak velocity with generic calliper
```
37
normal range of peak velocity of MPV
- 15-40 cm/sec
38
splenic vein - protocol
- color and spectral (anterior subcostal)
| - long axis
39
left hepatic - protocol
- color and spectral (anterior subcostal)
| - long axis
40
left portal vein - protocol
- color and spectral
- subxiphoid window
- long axis
- not doing velocity
41
right hepatic vein - protocol
- color and spectral
- right intercostal window
- long axis
- closest to diaphragm
42
middle hepatic vein - protocol
- color and spectral
- midline subxiphoid
- intercostal
- long axis
43
right portal vein - protocol
- color ade spectral
- coronal intercostal
+ same as MPV
- not doing velocity
44
hepatic artery - protocol
- color and spectral (coronal intercostal)
- same window and area as MPV
- measure PSV
- patient may hold breath for this image only
45
splenic vein - protocol
- closer to heart
| - more crazy waveform
46
IVC - protocol
- subxiphoid
- long axis
- close to diaphragm
47
flow tips - portal vs vein
- portal venous flow is slower than hepatic vein so adjust flow
48
sweep speed
- medium
49
portal vein baseline
- move down a little
50
hepatic vein baseline
- move up slightly
51
intercostal scanning tips
- rotate transducer to go between ribs
| - point transducer indicator toward patient right scapula
52
portal hypertension
- elevated pressure in portal venous system
| + impedes blood flow through the liver
53
portal hypertension - causes
- volume overload
| - increased resistance to flow
54
three classifications of portal hypertension
- pre-hepatic
- intrahepatic
+ most common
- post hepatic
55
pre-hepatic portal hypertension - casues
- portal of splenic thrombosis
- portal or splenic invasion
- extrinsic compression by a tumor
56
intrahepatic portal hypertension - causes
- hepatocelluar disease
+ CIRRHOSIS
+ hepatitis
+ fatty infiltration
57
post hepatic portal hypertension - causes
- thrombosis of hepatic veins (Budd chiari)
- thrombosis of IVC
- congestive heart failure
- right sided heart disease
58
risk factors of portal hypertension
- chronic liver diseases that precedes fibrosis or cirrhosis
- heart disease resulting in increased right sided heart pressures
59
chronic liver disease that precedes fibrosis or cirrhosis
- viral hep (chronic hep B or C)
- alcoholic liver disease
- autoimmune disorder
+ primary biliary cirrhosis, primary sclerosing, cholangitis
- metabolic and genetic disorders
+ hemochromatosis, Wilsons disease
- schistosomiasis
- non alcoholic steatohepatitis NASH
- sarcoidosis
60
heart disease leading to increased right sided heart pressure s
- tricuspid regurge
- congestive heart failure
- constrictive pericarditis
61
patient clinical signs - portal hypertension
- ascites (abdominal distention)
- splenomegaly
- GI bleed
- JAUNDICE (COMMON SIGN OF CIRRHOSIS)
- abnormal LFTs
62
can patients be asymptomatic with portal hypertension
- yes
63
manifestations of signs and symptoms associated with underlying disease - portal hypertension
- pancreatitis
| - liver diseases
64
patient history - portal hypertension
- could have variceal hemorrhage (hematemesis and melena)
| - bacterial peritonitis
65
physical exam of patient would see - portal hypertension
- jaundice (if liver sufficiently impaired)
- splenomegaly (could lead to low platelet counts)
- dilated abdominal wall veins
- hepatic encephalopathy (confusion due to poor liver function)
66
ultrasound evaluation would document - portal hypertension
- portal vein diameter > 13mm
- cavernous transformation (intraabdominal collaterals)
- portocaval anastomoses
- dilation/ recannalization of umbilical vein
- splenomegaly > 13cm
67
duplex eval - patency of vessels (collaterals too)
- color doppler
+ flow or lack of flow
- power doppler
+ tortuous vessels and collaterals
68
duplex eval - direction of flow
- color and spectral
| - possibility of reversed flow in portal/splenic veins
69
duplex eval - loss of phasic variation
- special tracing
- in response to respiration
- Changs to biphasic with progression to flow reversal
+ increased pressures
70
duplex eval - presence or absence of thrombosis
- 2D
- color
+ decease or absent of flow
+ not indicative of hypertension in patients with chronic liver disease
71
duplex eval - PV velocity
mean velocity 15-18 cm/s
72
pulsatile and dilated IVC mean what
congestive heart failure
73
portal vein thrombosis - primary condition
```
- can be found in patients with
+ liver disease
+ hypercoagulable states
+ intestinal inflammation
= appendicitis, diverticulitis,
- causes increased resistance in portal venous circulation
```
74
ultrasound findings - portal vein thrombosis
- enlarged PV
- lack of flow or decreased flow
- collateral flow
- enlarged hepatic artery and increased flow
- tumor
- portal vein occlusion
75
PVT - enlarged PV
- look for thrombus in lumen
| + variable echogenicity
76
PVT - lack of flow or decreased flow
- spectral color or power doppler
77
PVT - collateral flow
- chronic PV thrombosis
| - cavernous transformation/shunts
78
PVT -tumor
- invasion of portal vein
- typically hepatocellular and pancreatic carcinoma
- presence of arterial flow within thrombosis
- partial blockage
+ at site of obstruction = increase speed and disturbed flow patterns
+ distal to obstruction = continuous flow no respiratory changes
79
PVT - portal vein occlusions
- usually permanent
| - fibrotic changes cause vessel to virtually disappear
80
three pitfalls of scanning for PVT
1) undetected anechoic thrombus/tumor
2) low velocity flow undetected
3) inadequate doppler angle precluding detection of flow
81
hepatic vein occlusion (budd chiari syndrome) - causes
* post hepatic portal hypertension
- thrombosis
+ increases hypercoagulability
= oral contraceptives, polycythemia, hemoglobinuria
- compression
- tumor invasion
- cirrhosis
- membraneous obstruction of IVC
82
hepatic vein occlusion - signs and symptoms
- hepatomegaly
- abdominal pain
- acute development of ascites
- abnormal liver function tests
- splenomegaly and collaterals may be evident in chronic cases
83
hepatic vein occlusion - ultrasound findings
- hepatomegaly
- caudate lobe hypertrophy
- thrombus or tumor in HV or IVC
- ABSENCE OF FLOW
- if veins are narrow
+ focal elevation of velocity
+ turbulence
- deep liver
+ segmental lack of flow and bicolor
- collaterals
+ connecting patent HV with the portal system
+ bypasses the occluded segment
- IVC should be evaluated to rule out thrombus or tumor causing secondary obstruction to hepatic veins
84
normal portal vein - ultrasound
- low velocity (15-30cm/s)
= hepatopedal flow
- respiratory variations
85
hepatic artery - ultrasouns
- low resistance flow
| - PSV 70-150 cm/s
86
hepatic vein - ultrasound
- multiphase flow
87
right sided heart failure/tricuspid regurge - ultrasound
- increase HV pulsatility
| - pulsatile PV and IVC
88
portosystemic collaterals and shunts
- obstruction of major vessels forces blood to take a secondary route
- flow directed toward mesenteric, splenic and portal veins
89
collaterals
- preexisting vessels
- blood flow completes circulation back to IVC
- secondary vessels dilate
- high risk rupturing
90
most common collateral routes
- at esophagus
+ near the stomach
+ under the left lobe of the liver
+ near the spleen
91
coronary vein (left gastric vein)
- > 7mm
- most common collateral
+ reversed flow in 80-90% of PH cases
- can progress to esophageal varices
- presence clinically important
+ implies increased risk for variceal hemorrhage
92
coronary vein - location
- anterior to CA bifurcation
- posterior to common hepatic artery or splenic artery
- follows oblique path travelling superior to the left of portosplenic confluence
93
umbilical vein
- remnant of the umbilical vein
+ located in the lig teres
- from the umbilicus to the tip left portal vein
- hepatofugal flow
- normally measure less than 3mm no blood flow
94
most common collaterals
- coronary vein
- umbilical vein
- splenorenal vein
95
surgical shunts
- decompress the portal system
- surgical or endovascular
- in severe cases of portal hypertension or cirrhosis
96
surgical shunts effective for
- reducing ascites
- preventing hemorrhage from gastroesophageal varices
- improving quality of life of patio nest with severe cirrhosis
97
trans jugular intrahepatic portosystemic shunt TIPS
- most common
- metallic expandable stent
+ installed percutaneously
+ IJV into HV through liver tissue to PV
+ duplex US to assess
- success 90%
- subject to high rate of stenosis or occlusion
- compensatory increased flow seen in HA
98
TIPS - early complication
- stenosis or thrombosis
| - first few weeks of stent placement usually due to thrombosis
99
TIPS - late complication
- neointimal hyperplasia invading stent
100
TIPS - most common site of stenosis
- hepatic vein end
101
post surgery
- baseline study
| - regular follow up
102
TIPS - normal ultrasound
- patent TIPS
- TIPS velocity range 90-190cm.s
- PV peak velocity 30cm/s
- similar velocities at each end
- pulsatile wave form
- MPV caliber up to 15mm
- PV and Sv - hepatofugal flow
- RPV/LPV flow towards stent
103
TIPS - abnormal ultrasound
- no flow
- focal area narrowing
- velocity gradient > 100cm/s at stenosis
- TIPS velocity < 50cm/s
- PV velocity <30cm/s
- continuous flow
- RPV?LPV flow away from stent
104
transplant liver
- treatment for end stage liver disease
| - duplex US used inure and post op assessment of patient s
105
pre op liver transplant scan
```
- assessment for patency of
+ portal vien
+ hepatic artery
+ hepatic vein
+ IVC
- detect tumors in liver or surrounding tissue
- biliary tree status
```
106
post op liver transplant scan - performed
- within 24 hours post op
| - follow up at 1 6 and 12 month
107
post op liver transplant scan - color and spectral
```
- confirms patency of all major vessels
+ hepatic artery (most important)
= RI : 0.5-0.8
= PSV : < 200 cm/s
= acceleration time : < 0.08 sec
- assess anastomosis sites
- flow direction and vessel size
+ portal vein normal up to 15mm
```
108
post op liver transplant scan - 2D
- liver parenchyma
- biliary tree
- perihepatic spaces
109
post transplant complications
- HA thrombosis
- stenosis
- viability of liver is critical to hepatic artery inflow
- hematoma
- abscess formation
- AV fistulas
110
HA thrombosis - liver transplant
- MOST COMMN
- within first 6 weeks
+ absence of flow
+ dampening of PSV
+ decreasing diastolic flow
- stenosis of anastomosis sites
- PV thrombosis, air (PV larger up to 15mm)
111
stenosis - liver transplant
- at surgical anastomosis
112
post op liver scan - doppler
- appropriate doppler angle critical
+ HA tortuous
+ sample along artery starting at celiac axis
113
portal hypertension sonographic signs
- ascites
- MPV diameter > 13mm
- splenic vein diameter > 10mm
- patent umbilical vien
- paraumbilical vein > 2.5. mm
- splenic length > 13mm
- portal vein thrombosis
- +/- cavernous transformation of MPV
- slow PV flow
- alternating retrograde/antergrade PV flow
- hepatofugal flow in portal/splenic vessels
- coronary vein retrograde flow
- esophageal varices
114
budd chiari (hepatic vein occlusion) - sonographic signs
- hepatomegaly
- caudate lobe hypertrophy
- decreased absent or reversed flow in any HV
- narrowed IVC
- thrombus in IVC or HV
- dampened HV spectral trace
- collaterals within liver tissue
115
congestive heart failure
- increased right heart pressure
- PV pulsatile
- HV increased pressure
+ W PATTERN
- dilated IVC