Module 5: DNA & Polypeptide Synthesis Flashcards
What is the first step of polypeptide synthesis?
A gene in the DNA is “switched on”.
What is the second step of polypeptide synthesis?
The gene is transcribed into a mobile copy called messenger RNA (mRNA).
What is the third step of polypeptide synthesis?
The mRNA undergoes some processing.
What is the fourth step of polypeptide synthesis?
mRNA exits the nucleus and moves to a ribosome in the cytoplasm.
What is the fifth step of polypeptide synthesis?
The ribosome uses mRNA as a template to make a polypeptide from amino acids in the cytoplasm. This is called translation.
What is the last step of polypeptide synthesis?
The polypeptide is folded into a 3D shape to form a protein. This may involve the polypeptide being combined with other polypeptides or molecules.
What is RNA?
RNA is a type of nucleic acid that assists in the process of polypeptide synthesis. It has one strand and instead of deoxyribose sugar, it has ribose sugar.
What is thymine replaced with in RNA?
Uracil.
What sugar does RNA have?
Ribose sugar.
What is transcription?
The creation of messenger RNA (mRNA), using one strand of DNA as a template.
What is the role of polymerase?
It is responsible for transcribing the base sequence onto the mRNA, to be transferred to ribosomes in the cytoplasm.
Why is mRNA important?
mRNA is important as it transcribes the genetic instructions in DNA for making a polypeptide. Being mobile, mRNA then takes these instructions to the ribosomes where they are translated into forming a protein.
Where does translation occur?
Ribosomes in the cytoplasm.
Describe the structure of tRNA.
A “t” molecule, with three nitrogenous bases on one end, and its corresponding amino acid on the other.
What is tRNA?
tRNA is a form of RNA that stands for transfer RNA. It will temporarily bind to the codon in the mRNA, ensuring the correct sequence of amino acids forming the polypeptide chain.