Module 5: Cell Replication Flashcards

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1
Q

What are the two main phases of the cell cycle?

A

Interphase and M phase (mitosis).

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2
Q

What are the three subprocesses of interphase?

A

G1, S phase, and G2.

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3
Q

What occurs in G1 of interphase?

A

Cellular growth.

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4
Q

What occurs in S phase of interphase?

A

Cellular growth and DNA replication.

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5
Q

What occurs in G2 of interphase?

A

Cellular growth.

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6
Q

What types of organisms have a cell cycle of growth and division?

A

Multicellular organisms.

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7
Q

Which is the shortest phase of the cell cycle?

A

M phase.

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8
Q

What are the four stages of mitosis?

A

Prophase, Metaphase, Anaphase, and Telophase.

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9
Q

What is PMAT?

A

The four stages of mitosis. Prophase, metaphase, anaphase, and telophase.

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10
Q

What occurs in prophase?

A

The chromosomes condense to become visible and the nuclear envelope begins to break down. The mitotic spindle begins to form.

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11
Q

What occurs in metaphase?

A

The chromosomes align in the middle of the cell and the centromere of each chromosome becomes attached to a spindle fibre.

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12
Q

What occurs in anaphase?

A

The two sister chromatids of each chromosome move away from each other towards the opposite poles of the cell. The chromatids are now called daughter chromosomes.

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13
Q

What occurs in telophase?

A

The cell prepares to split in two by forming a nuclear envelope around each set of chromosomes and the spindle disappears.

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14
Q

What is cytokinesis?

A

Cytokinesis divides the cytoplasm in two, each with its own nucleus. After cytokinesis, two genetically identical daughter cells have formed.

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15
Q

What is mitosis?

A

The type of cell division used for growth and repair. It allows one parent cell to become two genetically identical daughter cells.

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16
Q

Describe chromosome structure in G1 of interphase.

A

During the G1 phase, chromosomes exist as a single chromatid, made of a single DNA molecule.

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17
Q

Describe chromosome structure in S phase of interphase.

A

Each chromosome is made of two identical chromatids. The two DNA molecules are joined together at the centromere to make an “X” shape.

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18
Q

What are centromeres?

A

The centromeres are organelles that assist the process of mitosis. They have thread-like structures called microtubules that form mitotic spindles, which control chromosomal movement in mitosis.

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19
Q

Describe chromosome structure in M phase of the cell cycle.

A

During the M phase, cell division occurs by mitosis. The two chromatids separate into two identical daughter chromosomes.

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20
Q

When do chromosomes have an “X” shape?

A

After the S phase.

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21
Q

What is the mid-point of a chromosome called?

A

The centromere.

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22
Q

How many chromosomes does a human body cell have?

A

46

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23
Q

How many homologous pairs of chromosomes does a human body cell have?

A

23

24
Q

How many chromosomes does a human gamete have?

A

23

25
Q

How many pairs of chromosomes does a human gamete have?

A

None.

26
Q

Where do the two chromosome copies in diploid cells come from?

A

One from each parent.

27
Q

What are “homologous chromosomes”?

A

A pair of corresponding chromosomes.

28
Q

Which human cells are haploid?

A

Sex cells (gametes).

29
Q

Which human cells are diploid?

A

Body cells, excluding gametes.

30
Q

How does mitosis contribute to the continuity of a species?

A

Allows growth and repair in multicellular organisms, thus allowing them to survive to reproduce. Also involved in some forms of asexual reproduction, e.g. budding in yeast,
amoeba.

31
Q

How does meiosis contribute to the continuity of a species?

A

Allows sexual reproduction and increases genetic variety in the offspring.

32
Q

Can crossing over occur in mitosis?

A

No

33
Q

Can crossing over occur in meiosis?

A

Yes

34
Q

How many times does cytokinesis occur in mitosis?

A

Once

35
Q

How many times does cytokinesis occur in meiosis?

A

Twice

36
Q

What is meisosis?

A

Meiosis is a type of cell division that creates gametes; it only occurs in the reproductive organs of organisms that reproduce sexually.

37
Q

How many daughter cells does meiosis produce?

A

4

38
Q

Are daughter cells produced be meiosis identical to each other?

A

No

39
Q

What happens during Meiosis-Ⅰ?

A

Homologous chromosomes are lined up in the middle of the cell, and separated.

40
Q

What happens during Meiosis-ⅠⅠ?

A

Sister chromatids are lined up in the middle of the cell, beore being separated.

41
Q

What does meiosis produce?

A

4 genetically unique haploid cells.

42
Q

What are alleles?

A

A variant of a gene for a particular trait.

43
Q

What is a gene?

A

A relatively small section of DNA that is a distinct inheritable unit. For example, it may code for a specific protein.

44
Q

What is crossing over?

A

A process that occurs during meiosis where homologous chromosomes exchange some genetic material.

45
Q

Describe the shape of DNA.

A

The shape of DNA is known as a double-helix, consisting of two strands that wrap around each other.

46
Q

Where is DNA found in eukaryotic cells?

A

In eukaryotic cells, it is wrapped tightly into coiled structures called chromosomes. This is found in the membrane-bound nucleus of all cells.

47
Q

Describe DNA in prokaryotic cells.

A

In prokaryotes, DNA is in a single circular strand, found primarily in the nucleoid region. However, some genetic material can be found in plasmids.

48
Q

Why is DNA replication important?

A

It ensures that each new cell formed receives a complete genetic code; this is essential for correct function.

49
Q

How is DNA replication controlled?

A

DNA replication is controlled in cells by various enzymes and other proteins.

50
Q

What is the first step of DNA replication?

A

At the beginning of replication, helicase (an enzyme) unwinds the two strands, creating a replication fork. One new strand is called the leading strand, and one the lagging strand.

51
Q

What enzyme helps unwind DNA during replication?

A

Helicase.

52
Q

Describe the structure of the “lagging strand” in DNA replication.

A

It is made of multiple pieces that are joined together.

53
Q

Describe the structure of the “leading strand” in DNA replication.

A

The leading strand is made of one continuous piece.

54
Q

What is the role of DNA polymerase?

A

DNA polymerase assists this process of nucleotides being added to the new strands, along with many other enzymes/proteins.

55
Q

What are the three sources of varitaion in sexual reproduction?

A

Fertilisation, independent assortment, and crossing over.

56
Q

What is independent assortment?

A

Meiosis randomly separates the homologous chromosomes.

57
Q

Is cell replication by mitosis important for the continuity of a species?

A

Yes. In asexual reproduction, offspring are created using mitosis. In all multicellular species, offspring need mitosis for growth and repair in order to survive, so that they can reproduce.