Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHGY > Module 5 > Flashcards

Module 5 Flashcards

1
Q

Bind to actin filament –> allows movement

A

Actin-Binding Motor Proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Actin filaments linked to NON ACTION structural proteins

A

Membrane Anchors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

side-to-side linkage –> form actin filaments

A

Cross-linking proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Bind to actin polymer –> sever/ induce disassembly

A

Severing & Depolymerizing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Bind to + or - end –> stabilizing polymer –> prevents disassembly/further assembly

A

Capping protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Bind to actin polymer –> increase stability, allowing new branch growth

A

Nucleating protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Bind to actin filament –> allows movement

A

Actin-Binding Motor Proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Domains of Motor Proteins

A

Motor, regulatory, tail

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Motor Domain

A

-1 heavy chain
-binds to ATP and actin filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Regulatory Domain

A

-1 heavy, 2 light chains
-Moves back and forth as myosin moves along actin filament

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tail Domain

A

Binds to other cellular proteins OR other myosins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Movement of Actin binding motor proteins

A
  1. HYDROLYSIS
    ATP –> ADP + Pi causes conformational shift swinging the domain
  2. ACTIN BINDING
    motor domain +actin filament –> releases Pi causes conformational change pulling myosin along actin filament

ADP released –> binding of new ATP –> myosin unbinds from actin filament

  1. MOVEMENT
    Moves towards + (barbed) end
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Actin Filaments responsible for migration

A

Filopodia
Lamellipodia
Stress Fibre

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Filopdia

A

-thin
-parallel
“+” faces membrane
-extends in direction of intended movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lamellipodia

A

-larger
-sheet-like bundles of actin filament
-polar (+ end faces membrane)
-form broader structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Stress Fibres

A

-form around interns
-resemble filopodia BUT
“+” end faces cytosol
-rich in MOTOR proteins (move cell forward)

17
Q

Cyclin

A

Proteins associated with progression of cell cycle

18
Q

CDKs

A

bind to cyclin to ACTIVATE and TRIGGER next stage of cell cycle

19
Q

p53

A

tumour suppressor protein (prevents division and uncontrollable replication)

initiates APOPTOSIS in damaged DNA of cells

20
Q

Mitosis Phases

A

Prophase
Prometaphase
Metaphase
Anaphase
Telophase

21
Q

Before Mitosis

A

INTERPHASE
-growing/preparing for division
-DNA replication occurs

22
Q

After Mitosis

A

CYTOKINESIS
-in mammalian cells contractile ring forms (cleavage furrow) splitting into 2 identical daughter cells

23
Q

The cell cycle

A

Mitotic Spindle Checkpoint
G1 Phase
G0 Phase
G1/S Phase
S Phase
S/G2 Checkpoint
G2 Phase
G2/M Checkpoint
M Phase

PHGY (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions