Module 5 Flashcards

1
Q

an order for medication issued by a physician, dentist or other properly licensed medical practitioner.
Designate a specific medication and dosage to be prepared by a pharmacist.
Are usually written on preprinted forms containing the traditional “Rx” (means “recipe”, “take thou”, or “you take”.)

A

Prescription

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2
Q

Are usually received by the pharmacist via telephone or by direct communication.
Pharmacists immediately reduces the order to a properly written form or computer entry.
Prescriptions are used in the outpatient, or ambulatory setting.

A

Prescription Orders

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3
Q

Prescriptions are…

A

▪ primary means by which prescribers communicate with pharmacists regarding the desired treatment regimen for a patient.
▪ written for infants, children, and elderly which also includes the age, weight and/or body surface area (BSA) of the patient.
▪ Medication orders are used in the inpatient or institutional health system setting.
▪ Prescriptions and inpatient orders are legal orders that can be used for medications, devices, laboratory tests, and procedures.
▪ Before dispensing the prescription or medication order, the pharmacist’s responsibility is to evaluate the prescription or medication order for appropriateness.
▪ This includes ensuring the correct drug, dose and dosage form, frequency, route of administration, duration of therapy and indication.

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4
Q

A prescription contains:

A

▪ NAME OF THE PATIENT
▪ DRUG NAME
▪ DRUG STRENGTH
▪ DRUG DOSAGE FORM
▪ QUANTITY PRESCRIBED
▪ DIRECTION FOR USE
▪ NAME, ADDRESS AND SIGNATURE
OF THE PRESCRIBER

ADDITIONAL INFORMATION:
▪ DATE OF ISSUE
▪ NUMBER OF REFILLS AUTHORIZED
▪ ADDRESS AND DATE OF BIRTH OF PATIENT
▪ PRESCRIBER’S DRUG ENFORCEMENT ADMINISTRATION(DEA) REGISTRATION NUMBER.

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5
Q

Medication Errors…

A

▪Typically contain similar information that would be included on a prescription.
▪This includes patient’s name, patient’s date of birth, medical record number, patient’s location and room number, date and time of order, drug name, dose, route, frequency, and duration; prescriber’s name and signature.

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6
Q

▪ Pharmacy is the art or practice of preparing and preserving drugs and of compounding and dispensing medicines according to the prescriptions of physicians.
▪ Compounding is a professional prerogative that pharmacists have performed since the beginning of the profession. Even today, the definitions of pharmacy include the preparation of drugs.

A

Extemporaneous Compounding

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7
Q

▪ is increasing for a number of reasons, including:
- the availability of a limited number of dosage forms for most drugs
- a limited number of strengths of most drugs, home health care, hospice, the non-availability of drug products/combinations, discontinued drugs, drug shortages, orphan drugs, new therapeutic approaches and special patient populations.
▪ Special populations includes:
- pediatrics, geriatrics, bioidentical hormone replacement therapy for postmenopausal women, pain management, dental patients, environmentally and cosmetic sensitive patients, sports injuries and
veterinary compounding, including small, large, herd, exotic, and companion animals.

A

Pharmaceutical Compounding

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8
Q

are unique professionals: well trained in the natural, physical, and medical sciences and sensitized to the potential tragedy that may result from a single mistake that may occur in the daily practice of their profession.

A

THE COMPOUNDING PHARMACIST

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9
Q

Compounding may hold different meanings to different pharmacists. It may mean

A

▪ the preparation of oral liquids, topical creams/ointments, suppositories
▪ the conversion of one dose or dosage form into another
▪ the preparation of select dosage forms from bulk chemicals
▪ the preparation of intravenous admixtures, parenteral nutrition solutions, pediatric dosage forms from adult dosage forms
▪ the preparation of radioactive isotopes; or the preparation of cassettes, syringes, and other devices with drugs for administration in the home setting.

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10
Q

There are different types of compounded prescriptions, including:

A

▪ Isolated
▪ Routine
▪ Batch prepared

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11
Q

is one the pharmacist is not expecting to receive nor expecting to receive it again.

A

Isolated prescription

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12
Q

is one the pharmacist may expect to receive in the future on a routine basis, and there may be some benefits to product quality to standardize preparations like this (ie, preparation protocols on file).

A

Routine prescription

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13
Q

is one in which multiple identical units are prepared as a single operation in anticipation of the receipt of prescriptions.

A

Batch-prepared prescription

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14
Q

Evaluating the feasibility of Batch compounding:
▪ ECONOMIC CONSIDERATIONS—There are at least two different economic considerations in making the decision to compound prescriptions; these include:

A

(1) pharmacist compensation
(2) health-care costs

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15
Q

Compounding Factors:

A

STABILITY
QUALITY CONTROL
TRAINING AND EXPERIENCE
EQUIPMENT
ENVIRONMENT
FORMULAS
CHEMICALS AND SUPPLIES

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16
Q

One key factor in compounding prescriptions is stability. The more common types of stability of which compounding pharmacists should be aware
include chemical, physical, and microbiological.
▪ Whereas commercially manufactured products are required to possess an expiration date, compounded products are assigned a beyond-use date.

A

STABILITY

17
Q

One of the fastest growing and most important areas of pharmaceutical compounding is that of quality control. Quality must be built-in to the preparation from the beginning steps to evaluating the final preparation.

A

QUALITY CONTROL

18
Q

Pharmacists involved in upgrading and increasing the traditional aspects of extemporaneous compounding need to keep current with all tools of their trade, retrieve the old from storage, and put in a bit of practice using their scientific background and their art before they will be comfortable in exhibiting their skills.
▪ The extemporaneous compounding by pharmacists meets the additional needs of patients that traditionally manufactured products do not meet.

A

TRAINING AND EXPERIENCE

19
Q

The equipment needed will be determined by the type and extent of the services one chooses to provide. Many pharmacies already have clean air environments (eg, laminar air flow hoods, isolation barrier systems) where aseptic compounding of sterile solutions is performed.
▪ A balance, preferably electronic, is essential. Ointment slabs (ie, pill tiles), along with spatulas of different types and materials, should be purchased. A few mortars and pestles (ie, glass, ceramic, plastic) and some glassware should be secured.

A

EQUIPMENT

20
Q

A separate area for traditional compounding is recommended, rather than simply cleaning off a small area of the dispensing counter.
▪ The compounding pharmacist needs a clean, neat, well-lit and quiet working area.
▪ If aseptic compounding is considered, a clean air environment (e.g., laminar air flow hood, isolation barrier system) should be used. The actual facility to be used depends on the level and volume of compounding to be done.

A

ENVIRONMENT

21
Q

Consistency of the compounded product is
important.
▪It should be developed or obtained and tried to
assure that each time an extemporaneous product is prepared, the methods used, ingredients added, and the order of steps is documented

A

FORMULAS

22
Q

If one is going to prepare a topical product, a vehicle (eg, cream, ointment, gel) and the active
ingredients (eg, either finely ground product from an available tablet or injection or pharmaceutical-grade chemicals) would be required.

▪ One needs proper dispensing containers for the medication. In short, a relationship with providers that carry chemicals and supplies is important.

A

CHEMICALS AND SUPPLIES

23
Q

Compounding Types:

A

▪ AMBULATORY-CARE COMPOUNDING
▪ HOSPITAL PHARMACY COMPOUNDING
▪ VETERINARY COMPOUNDING
▪ NUCLEAR PHARMACY COMPOUNDING

24
Q

Compounding Types:

A

▪ AMBULATORY-CARE COMPOUNDING
▪ HOSPITAL PHARMACY COMPOUNDING
▪ VETERINARY COMPOUNDING
▪ NUCLEAR PHARMACY COMPOUNDING

25
Q

If individuals can walk, they are considered mobile or ambulatory (ie, they are not bedridden).
Consequently, most pharmacists are involved in ambulatory care, and most ambulatory patients are outpatients.

A

AMBULATORY-CARE COMPOUNDING

26
Q

The ever-present responsibility of the health-care industry is to provide the best available
care for the patient, using the best means to do so, and providing that care in a conducive environment

A

HOSPITAL PHARMACY COMPOUNDING

27
Q

Veterinary compounding is necessary for many reasons. For example, with multiple species ranging from small to large it would be impossible to practice effective medicine without compounded product.

A

VETERINARY COMPOUNDING

28
Q

Radioactive drugs, commonly referred to as radiopharmaceuticals, are a special class of drugs that are regulated by the FDA.

▪ Most radiopharmaceuticals are administered intravenously so a nuclear pharmacist must be proficient at maintaining aseptic conditions during compounding.
▪ The most common setting for the provision of radiopharmaceuticals by nuclear pharmacists is a commercially centralized nuclear pharmacy.
▪ Radiopharmaceuticals are generally prepared early in the morning and unit
doses delivered to hospitals in the region surrounding the nuclear pharmacy.

A

NUCLEAR PHARMACY COMPOUNDING

29
Q

Indeterminate quality. More refined, but still of unknown quality

A

Technical or commercial CP (chemically pure)

30
Q

Meets minimum purity standards; conforms to tolerances set by the SP/NF for contaminants dangerous to health

A

USP/NF

31
Q

High purity, conforms to minimum specifications set by the Reagent Chemicals Committee of the American Chemical Society

A

ACS reagent

32
Q

Very high purity
Solvents purified for use in high-performance liquid chromatography (HPLC); very high purity

A

Analytical reagent HPLC

33
Q

Very high purity

A

Spectroscopic grade

34
Q

Highest purity: required for accurate volumetric analysis) (for standard solutions)

A

Primary standard