Finals Reporting Flashcards

1
Q

systematic assessment of a patient’s medication management

aim:
optimize quality use of medicines minimize medication-related problems.

A

MEDICATION REVIEW

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2
Q

a multidisciplinary responsibility that ensures the ongoing safe and
effective use of medicines at
all stages of the medication
management pathway.

A

MEDICATION REVIEW

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3
Q

TYPES OF MEDICATION REVIEW

A

MEDICATION ORDER REVIEW
MEDICATION ADHERENCE REVIEW

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4
Q

review of individual medication orders and/or prescription validity. It may take place w/o the patient present.

A

MEDICATION ORDER REVIEW

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5
Q

review of a patient’s medicine-taking behavior (how they actually take their medicines and what their beliefs about medicines are).

A

MEDICATION ADHERENCE REVIEW

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6
Q

comprehensive review of a patient’s medicines in the context of their clinical conditions. Partnering with the patient/carer is essential.

A

clinical medication review

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7
Q

Conducting ______ medication reviews can optimize the medications used and reduce medicine-related problems.

A

evidence-based

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8
Q

In conducting amedication review it should be based on the ______.
-knowledge of processes for managing medicines,
-therapeutic knowledge on medicines use,
- ability to effectively communicate

A

clinicians’ knowledge and skill

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9
Q

The delivery models for medication review are just the same across health service organizations.

T or F

A

F

may vary across

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10
Q

Patients with a higher risk of experiencing medication-related harm should be given priority.
Risk assessment and stratification should be based on evidence and local organizational priorities.

T or F

A

T

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11
Q

A reduction in efficacy due to an
interaction can sometimes be just as
harmful as an increase.

T or F

A

T

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12
Q

A reduction in efficacy due to an
interaction can sometimes be just as
harmful as an increase.

T or F

A

T

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13
Q

it is said to occur when the effects of one drug are changed by the presence of another drug, herbal medicine, food, drink or by some environmental chemical agent.

A

interaction

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14
Q

The more drugs a patient takes the
lesser the likelihood that an adverse
reaction will occur.

T or F

A

F

greater

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15
Q

Drug interaction incidence is
expected to be higher in the adults
because ageing affects the functioning of the kidneys and liver.

T or F

A

F

Elderly

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16
Q

Treating patients with more than one drug at a time is extremely risky. Some quite essential drug interactions remained virtually unnoticed for many years.

T or F

17
Q

5 Patient factors contributing to DI:

A

Age
Drug dose
Serum drug level
Drug metabolism
Polypharmacy

18
Q

_____interactions are those that can affect the processes by which drugs are absorbed, distributed, metabolized and excreted (the so- called ADME interactions).

A

Pharmacokinetic

19
Q

Drug Absorption Interactions:

A
  • Effects of changes in gastrointestinalI pH
  • Adsorption, chelation & other complexing mechanisms
  • Changes in gastrointestinal motility
  • Induction or inhibition of drug transporter proteins
    Malabsorption caused by drugs
20
Q

Drug Distribution Interactions:

A
  • Protein-binding interactions
  • Induction or inhibition of drug transport proteins
21
Q

Drug Metabolism (Biotransformation) Interactions:

A

Changes in first-pass metabolism
Enzyme induction
Enzyme inhibition
Genetic factors in drug metabolism
Cytochrome P450 isoenzymes & predicting drug interactions

22
Q

(involving oxidation, reduction
or hydrolysis), turn drugs into more polar compounds

A

phase I reactions (functionalization)

23
Q

coupling drugs with some other substance (e.g. glucuronic acid, known as glucuro- nidation) to make usually inactive compounds.

A

phase II reactions (conjugation)

24
Q

Drug Excretion Interactions:

A

Changes in urinary pH
Changes in active renal tubular excretion
Changes in renal blood flow
Biliary excretion & the entero-hepatic shunt

25
are those where the effects of one drug are changed by the presence of another drug at its site of action.
Pharmacodynamic interactions
26
If two drugs that have the same pharmacological effect are given together the effects can be additive.
Additive or Synergistic Interactions
27
pairs of drugs with activities that are opposed to one another.
Antagonistic or Opposing Interactions
28
number of drugs with actions that occur at adrenergic neurons can be prevented from reaching those sites of action by the presence of other drugs.
Drug or Neurotransmitters Uptake Interactions
29
they prevent the reuptake of noradrenaline (norepinephrine) into peripheral adrenergic neurons.
tricyclic antidepressants
30
what type of drugs are most susceptible to alterations of GI absorption?
drugs that are not absorbed completely under optimum circumstances
31
by increasing Gl motility, may increase the rate at which another drug passes through the GI tract.
CATHARTICS
32
by decreasing GI motility, also may influence drug absorption
ANTICHOLINERGICS
33
increases motility of the upper GI tract,
METOCLOPRAMIDE