Module 4 sem 1 exam (action potential, neuroglial cells, and areas of brian) Flashcards
What is action potential
change in membrane polarity produced by voltage-gated ion channels
-only occurs where have high density of voltage-regulated gates
Describe the process of action potential across axon
- Arrival of current at axon hillock depolarises membrane
- Local pot. reach -55 mV threshold
- voltage-gated Na^+ channels open, Na^+ enters & depolarises cell, opening more channels=rapid pos. feedback cycle
- once membrane potential rises above 0 mV, Na^+ channels inactivated & close
- voltage peaks at +35 mV, membrane now [+ve] inside & [-ve] outside
- Slow K^+ channels open & outflow of K^+ repolarises
- K^+ channels remain open so membrane briefly hyperpolarised (more neg than RMP)
- RMP restored as Na^+ leaks in & K^+ removed by astrocytes
Describe some functions of neuroglia (support cells)
-protect neurons & help them function
-bind neurons together & form framework for nervous tissue
-prevent neurons from touching each other
Name the four types of CNS neuroglia
oligodendrocytes
ependymal cells
microglia
astrocytes
Describe the function of oligodendrocytes (Look at diagram)
form myelin sheaths in CNS- speed signal conduction
Describe the function of ependymal cells (Look at diagram)
secrete & circulate cerebrospinal fluid (CSF)
Describe the function of microglia (Look at diagram)
func: wander through CNS looking for debris & damage
Describe the function of astrocytes (Look at diagram)
func: secrete nerve growth factors
-convert glucose to lactate & supply this to neurons
Name the types of PNS neuroglia
schwann and satellite cells
Describe the function of schwann cells (Look at diagram)
assist in regeneration of damaged fibers and produce myelin sheath
Describe the function of satellite cells (Look at diagram)
provide electrical insulation around neurosoma
-regulate the chemical environment of neurons
Look at diagram of brain
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Describe broca’s area (and location)
-inferior prefrontal cortex usually in left hemisphere
-generates motor program for muscles of larynx, tongue, cheeks & lips for speaking & for hands when signing
-transmits program to primary motor cortex for commands to lower motor neurons that supply relevant muscles
Describe wernickes areas (and location)
-posterior to lateral sulcus usually in left hemisphere
-permits recognition of spoken & written language
-formulates phrases & transmits plan of speech to Broca’s area