Module 4 B Flashcards
Give 2 examples of cell specialisation in the human body
endothelial cells - form walls of blood vessels
muscle cells - cause peristaltic contractions
Key stages of animal embryogenesis
egg (cleavage - series of rapid cell divisions) –> bastula (gastrulation - cells move inwards to generate the germ layers) –> gastrula (organogenesis - formation of the tissues & organs of the body - neurulation) –> tail-bud stage –> differentiation commences & electrically active neural cells / muscles arise
Gastrulation & establishment of the germ layers
- Bastula (flattening)
- Cells at the base of the bastula begin to change shape
- Inward bulge formed by cells changing shape. Cells separate from outer layer & move inwards - form the mesoderm.
- Cells in the invagination form the endoderm layer.
- Endodermal cells extend, flatten, & undergo rearrangement to form a long thin tube - the gut
- Gastrula is formed. Future sites for the mouth & anus determined
blastopore = future site for anus
different types of tissue arise from the germ layers
- endoderm, mesoderm, ectoderm
Ectoderm
gives rise to external surfaces (e.g. skin) & the nervous system
Mesoderm
gives rise to many internal tissues like muscles, blood vessels, & other connective tissues
Endoderm
gives rise to the cells that line the alimentary canal & the various organs that branch off from it such as the lung, pancreas, & liver
Triploblastic animals
animals with 3 germ layers are called triploblast (most animals)
Diploblastic animals
animals lacking a mesoderm have 2 germ layers & include cnidarians like jellyfish & hydra (only have endoderm & ectoderm)
A stem cell division produces. . .
a new stem cell and a daughter cell that
can subsequently differentiate into other cell types
Organogenesis
involves several morphogenic processes - cell movement, cell adhesion, changes in cell shape
– interactions B/W the germ layers
Organogenesis is the process of formation of organs from three germ layers
Cell potency
ability of cell to give rise to other cell types
Describe epithelial tissue
2-D sheets of cells that cover the body surface internal cavities, & internal tubes such as the alimentary canal
Function of epithelial tissue
provide a barrier function b/w the body & outside world & b/w compartments of the body
endothelia –> epithelial tissues that line blood vessels & are of mesodermal origin
Epithelial cell features
apico-basally polarized
cell-cell junctions
tight junctions
– prevent passage of
small molecules between cells
* adherens junctions and
desmosomes provide mechanical
support
* Gap junctions allow cell cell
communication
cell-matrix junctions
attach epithelial cells to the
underlying extracellular matrix
(ECM) (called the basal lamina)
Functions of epithelia
glands – secretion of hormones, enzymes, sweat
intestine – absorption of nutrients
skin – protection from mechanical damage, heat loss, microbes, & water loss
airways – beating of cilia to keep airways clear of mucus & dirt
Connective tissue
support & connect other tissues
- usually consist of a few cells that exist in & contribute to an EXTRA-CELLULAR MATRIC (ECM)
ECM
- an interlocking mesh of fibrous proteins within some ground material, usually liquid but solid in the case of bone
- embedded proteins like collagen & elastin are secreted by cells, often by the cells within the matrix
Examples of connective tissue functions
tendons – strong connection b/w muscles & bones
bone – rigid support & protection of delicate tissues
adipose – storage & metabolism of fats
blood – transport of oxygen & carbon dioxide, nutrients, immune cells
cartilage – rubbery / flexible; shock-absorbing; friction reducing
Nervous tissue
- processing info
- gather info about the external & internal env.
- control physiology & behaviour of body
NEUTRONS TRANSMIT ELECTRICAL SIGNALS CALLED ACTION POTENTIALS
GLIAL CELLS PROVIDE MECHANICAL & NUTRITIONAL SUPPORT FOR NEURONS
- do NOT generate action potentials (e.g. Schwann cell)
3 types of neurons
- sensory neurons
- interneurons
- motorneurons
sensory neurons
generate electrical signals based on dif. stimuli (e.g. touch receptors) – output to neurons
interneurons
take input from neurons - output to other neurons
motorneurons
take input from neurons - output to muscles
examples of sensory neurons
- pressure receptors in skin
- stretch receptors in muscle
- olfactory receptors in nose
- photoreceptors in eye
Muscular tissue (3 types) – generating contractile force
- skeletal
- cardiac
- smooth
skeletal muscle
connects to the skeleton & generates voluntary movements of the body
cardiac muscle
contraction of the heart under involuntary control
what causes muscle contraction?
caused by an ATP-dependent motor protein comprised of myosin filaments pulling on actin filaments - contraction is activated by electrical signals
smooth muscle
surrounds internal organs - mainly under involuntary control
Integumentary system
provides a barrier to outside environment (skin)
Respiratory system
gaseous exchange