Module 4 Antepartum Canvas Flashcards
What is Hegar’s sign?
the unusual compressibility of the lower uterine segment at 4-6 wks GA
*probable sign of pregnancy
Explain where you would expect the fundus as different gestations.
Pelvic organ until 12 weeks!
16 weeks-midway between symphysis pubis and umbilicus
20 weeks-at umbilicus
After 20 weeks, measure in cm from pubic bone
Patients with severe N/V in 1st trimester may have what condition?
Subclinical hyperthyroidism
the alpha subunit of hCG is able to stimulate the thyroid gland as though it were TSH. (crazy!)
How does HR and BP change in pregnancy?
HR increases by 10 BPM
BP gradually decreases then returns to prepregnancy level in weeks 22-24
What murmurs are common and benign in pregnancy?
-mild pulmonic or tricuspid regurgitation
-systolic ejection murmur
-3rd heart sound
How should the NP care for a patient with pre-existing cardiomyopathies?
REFER PROMPTLY TO A PHYSICIAN!!!
What are the key hematological changes of pregnancy?
-pregnancy is a hypercoagulable state
-Protein S levels fall
-Activated protein C levels fall
What is the gold standard for diagnosis of IDA?
serum ferritin
How can physiologic dyspnea be distinuished from pathologic?
-Physiologic dyspnea can be distinguished from pathologic dyspnea by respiratory rate
-Tachypnea is a sign of possible respiratory compromise
What causes the GI changes in pregnancy?
Progesterone relaxes the smooth muscles, resulting in decreased peristalsis
What thyroid change is normal in pregnancy and what physical exam is abnormal
Overall enlargement is normal but nodules are ABNORMAL
Why is it important to maintain a euthyroid state in pregnancy?
-the fetus does not start secreting thyroid hormone until approx 18-20 wks gestation
-the fetus is depending on maternal thyroid hormone for critical metabolic functions
To assess the thyroid, what levels must be assessed?
TSH, FT4, T4
What hormone is the reason we screen all pregnant people for GDM and why?
hPL induces maternal insulin resistance & hepatic glucose formation
-these raise glucose levels in maternal circulation
What keeps the maternal immune system from rejecting the fetus?
The fetus is an allograft
Trophoblastic tissue does NOT express the cell membrane proteins that would stimulate an innate or cellular immune response
What are the steps of fertilization and implantation?
Fertilization (fusion of two haploid [23 chromosome] cells) -> Blastocyst (rapid cell division as it moves to the uterus) -> implants in the decidua
What is a normal AFI?
5-23.9
Oligo: <5
Poly: >24
How can neural tube defects be prevented?
Folic acid supplementation can reduce occurrence by 60-70%
Enriched cereal products and supplementation
400-800 mcg per day prior to conception through 8 weeks of pregnancy
Why should NTD screening be offered to everyone?
95% of cases occur in families that are previously unaffected
What is the gold standard of diagnosis of chromosomal disorders?
Evaluation by karotyping
Is an amniocentesis a screening or diagnostic test?
Diagnostic
What follow up testing should be offered for a positive NIPT?
CVS or amniocentesis
Why can the AFP only be done at a certain time?
This is a protein made by the fetal liver and is not produced until the second trimester
What diagnostic tests can be done during pregnancy?
CVS: between 10-14 weeks. Used for karyotyping. Does not detect NTD.
Amniocentesis: between 16-18 weeks. Used for karyotyping, aneuploidies and NTD
What is the preferred type of carrier screenign?
“Panethnic screening”
ALL PREGNANT PEOPLE ARE OFFERED CARRIER TESTING FOR CYSTIC FIBROSIS, HEMOGLOBINOPATHIES, AND SPINAL MUSCULAR ATROPHY IF THESE TESTS HAVE NOT BEEN PERFORMED PREVIOUSLY*
How should the NP respond when a patient has a positive genetic disorder test?
Refer to genetic gounselor, MFM, neonatologist.
Offer additional testing
Discuss pregnancy termination vs continuation
What BhCG and U/S results increase concern for an ectopic pregnancy?
BhCD less than 6500
TVUS: no intrauterine sac
What is the most accurate method for dating a pregnancy?
A first trimester ultrasound
At least one ultrasound is recommended for all pregnant people at what point in pregnancy?
In the first or early second trimester
What U/S measurement is used to determine GA in the first trimester?
CRL
What U/S measurement is used to determine GA in the second and third trimester?
BPD, HC, AC, FL
Explain presumptive signs of pregnancy
A person says: “I presume it might rain later today because I see some rain clouds here at my house.”
Weatherperson: “Ok…well, just because you see rain clouds, doesn’t mean it is 100% going to rain.”
Explain probable signs of pregnancy
Weatherperson says, “I’m looking here at my fancy weather doppler system and these patterns suggest that it will rain later today.”
Person: “OK…that is consistent with these rain clouds I’m seeing out my window.”
Explain positive signs of pregnancy
Weatherperson says (dressed in rain gear standing in a hurricane), “It is raining. It’s positively raining cats and dogs out here.”
Person: “OK. I see the weather person in the rain, and I’m looking out my window and it is raining. No doubt about it, it is raining!”
What is the only diameter of the pelvic inlet that can be clinical measured and what is the normal length?
Diagonal Conjugate
11.5cm or more