Module 4

Question 1

Early/acute side effects

Answer 1

Occur during the course of tx

Occur in tissues with high mitotic rate

Examples: inflammation, skin erythema/dry desquamation, denuding of mucous membrane

Question 2

Late/chronic

Answer 2

Can occur months or years after tx

May be long term, permanent and irreversible

Occur in tissue with slow mitotic rate

Examples: fibrosis, stenosis, hyperpigmentation, atrophy

Question 3

Fractionation

Answer 3

Dose/time relationship

Increase dose= risk

Question 4

Threshold

Answer 4

Severity increase with increase dose result in in clinical effect; below that there may be no effect

Question 5

Therapeutic ratio

Answer 5

The goal of RT is to destroy cancer cells while maintaining the integrity of normal tissue

Question 6

Tolerance

Answer 6

That dose which produced is an acceptable probability of treatment complications

Question 7

Dry desquamation

Answer 7

Shedding of epidermis, basal cell renewal can’t keep up with cell loss

Question 8

Moist desquamation

Answer 8

Basal cells are destroyed and dermis is exposed