Module 4 Flashcards
What is the GBD?
Global Burden of Disease Project
What were the reasons for conducting the GBD?
Data on the burden of disease (and injury) from many
countries were incomplete
Available data largely focused on deaths; little information
on non-fatal outcomes (disability)
Lobby groups can give a distorted image of which
problems are most important
Unless the same approach is used to estimate the burden
of different conditions, it is difficult to decide which conditions are most important and which strategies may be the “best buys”
What are the aims of the GBD?
1. To use a systematic approach to summarize the
burden of diseases and injury at the population-level based on epidemiological principles and best available evidence
2. To take account of deaths as well as non-fatal
outcomes (i.e., disability) when estimating the burden of disease
What were the key sources of datas for this project?
‘Vital registration data’ (eg, NZ’s national
mortality and hospital discharge databases)
Disease surveillance system
Epidemiologic studies & surveys n Statistical models developed to get bestestimates when data were incomplete
What is a DALY?
DALY = Years of life lost to mortality (YLL) + Years lived with disability (YLD)
Stands for Disability-Adjusted Life Year
Give the DALY for a year of perfect health
0
Give the DALY for a year of life lost due to death
1
Give the DALY for a year with disability
between 0 and 1
What is a communicable disease?
infectious diseases and (The GBD project includes problems during pregnancy, childbirth, or very early life in this group)
What is a non communicable disease?
chronic diseases (e.g, heart disease, strokes, cancer, diabetes)
Explain Demographic transition
decline in fertility and mortality rates
observed in most developed and several developing countries
Explain epidemiological transition
characteristic shift in the composition of
causes of death and disability from communicable to non-communicable diseases
Explain risk transition
Changes in risks factor profiles as countries shift
from low- to higher income countries, where common risks for perinatal and communicable diseases (e.g., unhygienic water) are replaced by risks for non-communicable diseases (e.g., tobacco)
Explain double burden of disease
In many middle-income countries, previously common risks for
perinatal and communicable diseases co-exist with increasing risks for non-communicable diseases.
What are the key factors influencing the risk burden?
- How strong is the ‘causal’ association between the risk factor and health condition(s) (eg, relative risk)
- How common is the exposure to this risk in the population of interest? (eg, the prevalence of the risk factor in the population)