Module 4 Flashcards
What material is able to pass freely between odontoblastic zone into the dentine
Serum proteins
T/F, cell-free zone of weil is present during tooth dvlpment ?
F, not present
What are the 4 cell types found in pulp
Fibroblast, immune cells, undifferentiated mesenchymal cells, odontoCLAST
_________is the main cell type of pulp. It produces & maintains_________
Fibroblast, matrix
Sensory & Sympathetic nerves enter the pulp via________
apical foramen
What is the definition of aging in cellular level ?
Diminished ability to respond to stress
hydropic change means cellular_________
swelling
Lipofuscin is characterised under microscope by__________
Brownish or black dots depending on type of microscope
Hyaline changes is characterised under microscope by__________
cells becoming more reddish/pinkish
Hyaline changes is caused by__________in plasma cells
excessive production of immunoglobulins
List 3 functions of Astrocytes
List 3 functions of Microglia
List the function of Oligodendrocyte
List the 2 functions of Schwann cell
What is the function of dental pulp ?
To support living dentine (provide nutrients, sensory function, protection)
Wt cells in myelin of dental pulp?
Schwann cells
Wt is the difference between myelinated and unmyelinated?
Myelinated: faster (jumping nodes) for sharp pain
Unmyelinated: slower (continuous); dull ache
Wt is the type of neuron in dental pulp?
Pseudo-unipolar
What fiber is for mechanical nociceptors?
A-delta
Wt fiber for thermal nociceptors?
A-delta
Wt fiber is for polymodal nociceptors?
Non myelinated c fibers
Where is trigeminal ganglion located?
Meckels cave
Wt is the ganglion involved with trigeminal nerve other than trigeminal ganglion?
Mesencephalic nucleus of V
(Deep in brain)
Distinguish motor and sensory root of trigeminal nerve.
Motor: small, medial
Sensory: large, lateral
They both enter in the lateral aspect of pons
What is the major cell type in the pulp ?
Fibroblast
What is in odontoblastic zone in pulp?
Cell bodies of odontoblast, capillaries, unmyelinated axons
The brainstem reticular formation is responsible for_______ aspect of pain processing ?
Arousal`
Sialosis is characterised by the enlargement of__________due to___________
major salivary glands, acinar hypertrophy
Anaplasia means______________
Loss of differentiation
How long do neutrophils stay in circulation ?
~5 days
How long do neutrophils live in tissue ?
2-6 hrs
Overproduction of___________cause malaise. They are also resonsible for fever ?
IL1, IL6, TNF
Neurons of spinomesencephalic tract terminates at___________
midbrain periaqueductal grey
___________tract can amplify/lower the noxious sensory input ?
Spinoreticular
__________tract is responsible for the emotional quality of noxious stimuli ?
Spinothalamic
Spinothalamic tract codes for which 4 qualities of pain ?
Location, Intensity, Sensory, Emotional
Cell bodies of sensory nerve (trigeminal) are found in____________
Gasserian ganglion, mesencephalic nucleus of V
Trigeminal nerve leaves pons___________(location) ?
Laterally
Brainstem is comprised of_____________
Mid brain + Pons + Medulla
The (motor/sensory) root of trigeminal nerve is bigger in size ?
Sensory
Which glia is the immune cell of CNS ?
Microglia
Which glia provide neuron support to CNS ?
Astrocytes
Which of the following sensory modality is conveyed by unmyelinated nerves?
Fine touch
Proprioception
Vibration
Crude touch
Pain
Pain
What type of neurons are responsible for a dull aching pain?
Unmyelinated neurons with soma in the trigeminal ganglia
Unmyelinated neurons with soma in the dorsal root ganglia
Pyramidal neurons
Myelinated neurons with soma in the trigeminal ganglia
Myelinated neurons with soma in the dorsal root ganglia
Unmyelinated neurons with soma in the dorsal root ganglia
In the process of extravasation, leukocytes move into tissues from the vasculature:
Predominantly in venules
Essentially as monocytes on the first day post injury - neutrophils
Predominantly in arterioles
In response to the Fc fragment of IgG
Predominantly in venules
What is located in the axon terminal?
Nucleus
Post synaptic receptors
Nodes of Ranvier
Synaptic cleft
Neurotransmitters
Neurotransmitters
