Module 4 Flashcards
Units of measurement abbreviations
SI - international Roentgen - system Rad - milliroentgen Rem Gray - (mR) millirad (Gy) - (mrad) millirem Sievert - (mrem) milligray (Sv) - millisievert (mSv) microsievert (μSv)
Radiation Absorbed dose (D)
Amount of x-ray energy absorbed by a unit mass of tissue
- unit: Gray (Gy)
- SI unit joules per kilogram
- 1Gy = 100 rads
Equivalent Dose (HT)
Allows the different radiobiological effectiveness (RBE) comparison
Radiation weighting factor WR
represents different biological effects of different radiation on different tissues
the unit of equivalent dose allows comparisons to be made between one type of radiation and another
Effective Dose (E)
Conversion of dose to specific area to whole body is called the tissue weighting factor (WT)
E = H X WT
Unit: sievert (Sv)
measures the potential risk to health
Effective dose in dental radiography
Bitewing/periapical = 0.0003 - 0.022 mSv
Panoramic = 0.0027 - 0.038 mSv
Upper Standard occlusal = 0.008 mSv
Lateral cephalometric and other medical exposures = 0.0022 - 0.0056 mSv
chest lateral x-ray = 0.038 mSv skull lateral x-ray = 0.016 mSv barium swallow = 1.5 mSv CT scan (chest) = 1.4 mSv
Collective Dose
Measured in man - Sv
Collective dose = effective dose (E) x population
in the UK in 2008 the collective dose was calculated by the health protection agency to be more 24,700 man-Sv
Dose limits
International commission for radiological protection (ICRP) sets the annual maximum dose for limits for radiation workers
Classified Workers:
Old dose limits - 50mSv
Current dose limits - 20mSv
Non classified workers:
Old dose limits - 15mSv
Current dose limits - 6mSv
General public:
Old dose limits - 5mSv
Current dose limits - 1mSv
Estimated annual dose
the radiological protection division of the health protection agency estimates the annual doses from various sources.
Dose rates are a measure of the dose per unit of time
Average annual dose:
Cosmic radiation - 330
External radiation from earth crust - 350
Ionising radiation from foodstuff - 250
Radioactive waste - 1
Medical and dental diagnostics - 410
Risk factors
Intra oral film
traditional equipment - 1 fatal cancer in every 2 million
recommended equipment - 1 fatal cancer in every 20 million
panoramic radiograph - 1 in 1,000,000
The younger the patient the greater the risk
smoking 10 cigarettes a day - 1 in 200 natural causes aged 40 - 1 in 700 accidents in the home - 1 in 10,000 accidents on the road - 1 in 10,000 accidents at work - 1 in 50,000
Multiplication of risk according to age
Under 10 = x3 10-20 = x2 20-30 = x1.2 30-50 = x0.5 50-80 = x0.3 80+ = negligible
Biological effects - Direct action (damage)
energy from ejected electron (photoelectrons) or the x-ray photon is transferred to the cells DNA, RNA or protein enzymes. this direct action causes damage by rupturing the helix causing point mutation, the correct information is not passed on Can lead to: Abnormal replication Cell death Radiation induced malignancy Reproductive stem cell interaction Radio induced congenital abnormality
Biological effects - indirect action
Most common reaction as 80% of our body consists of water
when radiation hits the water molecules ionization occurs. this produces ions and free radicals.
free radicals combine to form
Hydrogen Peroxide (a cellular poison)
and
Hydroperoxyl radical (a toxic substance)
they can transfer excess energy to other molecules - breaking the chemical bonds
Deterministic Effects
- will definitely happen from a specific high dose of radiation
- severity increases with increased absorbed dose
- threshold dose exists, there will be no effect below this dose
- early tissue reactions happening shortly after exposure
- late tissue reactions appearing months or years after exposure
Stochastic Effects
- may happen with any level of radiation
- no safe dose level, no threshold dose has the possibility of an stochastic effect
- every dose has the possibility of an stochastic effect
- the lower the dose the less probability of damage
- type of damage can not be determined
- severity of the damage not related to dose size
- cancer induction
- heritable/genetic effects
Genetic Effects
Gene or chromosomes mutate can be spontaneous or caused by radiation
the damage of the DNA of the sperm or egg cells only happens if the reproductive organs are radiated this can lead to congenital abnormalities
no threshold dose - may happen