Module 3-Lecture 16 Flashcards
1
Q
What is the mean?
A
Our best guess or expected value
2
Q
How to calculate the mean?
A
The sum of colony counts multiplied by fraction of replicates
3
Q
What is the variable m?
A
Number of mutations
4
Q
What is the expected m
A
The mean number of mutations
5
Q
What is N?
A
Number of cells that could have mutated
6
Q
What is u?
A
Mutation rate
-the number of mutations that we expect to observe in 1 individual during 1 division
7
Q
How to calculate expected m
A
uN or uR
8
Q
What is the variable R?
A
R is the number of DNA replications during which mutations could have happened
9
Q
What does it mean by mutation rate?
A
Expected/mean number of mutations of a given type that occurs per unit of length
10
Q
What 2 things do we need to specify for mutation rate?
A
- Mutation type
- Unit length of replicated DNA
