Module 3: Cells Flashcards
The cell can be divided into three principal parts
Plasma (cell) membrane
Cytoplasm:
Cytosol Organelles (except for the nucleus)
Nucleus
a flexible, sturdy barrier that contains the cell cytoplasm
plasma membrane
describe the structure of the plasma membrane
composed of a double layer (bilayer) of phospholipid molecules with many protein molecules dispersed within it.
Which parts of the plasma membrane are hydrophillic vs hydrophobic
The surfaces of the membrane are hydrophilic due to the polar phosphate heads. The internal portion of the membrane is hydrophobic due to the nonpolar fatty acid tails
Integral proteins are firmly inserted into and extend across the lipid bilayer of the Plasma Membrane. Most of these proteins are glycoproteins
Most of these proteins are glycoproteins, which serve as channels (pores), transporters (carriers), receptors (recognition sites), or enzymes
Plasma membranes are what level of permeability
Plasma membranes are selectively permeable, meaning that some things can pass through and others cannot.
The lipid bilayer portion of the membrane is permeable to what and impermeable to what
The lipid bilayer portion of the membrane is permeable to small, nonpolar, uncharged molecules, but impermeable to ions and charged or polar molecules. This bilayer also is permeable to water.
Transmembrane proteins
act as channels or transporters increase the permeability of the membrane to molecules that cannot cross the lipid bilayer
Macromolecules pass through the plasma membrane by
vesicular transport
Intracellular fluid (ICF) is located
inside the cell
extracellular fluid (ECF) is located
outside the cell.
The types of extracellular fluid
Interstitial fluid
Plasma
Lymph
Solutes
substances dissolved in a solvent.
concentration gradient
the difference in the concentrations of a substance between two areas (e.g., the amount of water in your cells compared to the amount of water in the lake in which you are swimming, or the amount of sodium ions in extracellular fluid compared to the amount of sodium ions in intracellular fluid)
Vesicular transport involves
the formation of membrane-surrounded vesicles to move materials into or out of the cell by endocytosis or exocytosis.
Living cells use three passive transport processes
non-mediated (diffusion through the lipid bilayer and diffusion through a channel)
mediated (facilitated diffusion).
the random mixing of particles that occurs in a solution as a result of the kinetic energy of the particles
Diffusion
the random mixing of particles that occurs in a solution as a result of the kinetic energy of the particles
Diffusion
Diffusion is influenced by
Steepness of the concentration gradient
Temperature
Size or mass of the diffusing substance
Surface area
Diffusion distance
Movement of molecules or ions down a concentration gradient means
Movement from a region of high concentration towards region of low concentration
Most membrane channels are ion channels, allow
the passage of small, inorganic, hydrophilic ions
a solute binds to a specific transporter on one side of the membrane and is released on the other side after the transporter undergoes a conformational change
facilitated diffusion
This is the process by which glucose enters and leaves most human cells
facilitated diffusion
the diffusion of water molecules through a selectively permeable membrane. It is the movement of water (the solute) from an area of higher concentration to an area of lower concentration across the membrane.
osmosis
relates to the concentration of solutes outside of the cell relative to the inside of a cell, and how the solution influences the shape of body cells.
tonicity
the concentration of solutes outside of the cell is the same as that inside the cell. In such a solution, red blood cells maintain their normal shape.
isotonic solution
the concentration of solutes outside of the cell is less than that inside the cell. In such a solution red blood cells swell, and undergo hemolysis.
hypotonic solution,
the concentration of solutes outside of the cell is greater than that inside the cell. In such a solution, red blood cells shrink and undergo crenation.
hypertonic solution
an energy-requiring process that moves solutes such as ions, amino acids, and monosaccharides against a concentration gradient.
Active transport
an energy-requiring process that moves solutes such as ions, amino acids, and monosaccharides against a concentration gradient.
Active transport
molecules or particles that are too large to enter the cell by diffusion or active transport are brought into a vesicle formed from a section of the cell membrane.
endocytosis
molecules or particles that are too large to enter the cell by diffusion or active transport are brought into a vesicle formed from a section of the cell membrane.
endocytosis
, membrane-enclosed structures called secretory vesicles, which form inside the cell, fuse with the cell membrane and release their contents into the extracellular fluid.
exocytosis,
a small membranous sac that forms by budding off from a cell membrane.
vesicle
Two types of vesicular transport are:
Endocytosis
Exocytosis
The three main types of endocytosis are:
Phagocytosis
Pinocytosis (bulk-phase endocytosis)
Receptor-mediated endocytosis
the intracellular fluid, is the semifluid portion of cytoplasm that contains inclusions and dissolved solutes
Cytosol
Cytosol is composed mostly of
water, plus proteins, carbohydrates, lipids, and inorganic substances.
network of several kinds of protein filaments that extend throughout the cytoplasm and provide a structural framework for the cell.
cytoskeleton
cytoskeleton consists of
microfilaments, intermediate filaments, and microtubules.