Module 3 all topics Flashcards
outline the features of a (closed) double circulatory system. (humans)
blood travels twice through the heart for each circuit; pulmonary and systemic, oxygenated and deoxygenated blood don’t mix
outline the features of a (closed) single circulatory system (fish)
blood passes through the heart once, 2 sets of capillaries
outline the features of an open circulatory system
no blood vessels
haemolymph is pumped directly into haemocoel (body cavity)
blood flow can’t be regulated through vasodilation or vasoconstriction
no transport of carbon dioxide or water
state the order of layers that forms blood vessels (6)
lumen, endothelium, elastic layer, muscle layer, collagen
outline the composition of arteries, relating to their function
0.4-2.5cm
- mostly elastin: stretch to sustain high pressures of blood
- some smooth muscle
- some collagen
outline the composition of arterioles
30 micrometres
- mostly smooth muscle
- elastin
- collagen
outline the composition of veins, relating to their function.
- largest proportion is collagen
- contains smooth muscle: for vasodilation and vasoconstriction
- contains small proportion of elastin
outline the composition of venules
no elastin
no smooth muscle
only collagen
explain what can be observed from an ECG showing tachycardia, and explain what somebody suffering from tachycardia is experiencing
shorter distances between the high points
still evenly spaced out no irregularities
fast heart beat, over 100bpm
explain what can be observed from an ECG showing bradycardia, and explain what somebody suffering from bradycardia is experiencing
lowered resting heart rate
larger distances between peaks, still evenly spaced out, no irregularities
explain what can be observed from an ECG showing atrial fibrillation, and explain what somebody suffering from atrial fibrillation is experiencing
abnormal atria rhythm, ventricles lose regular rhythm
lots of little peaks, big peaks aren’t evenly spaced out
atria are contracting very fast, but don’t contract properly, impulses are passed onto atria which contract much less often- ineffective pumping of blood through the heart.
explain what can be observed from an ECG showing an ectopic heart beat, and explain what somebody suffering from this is experiencing
- mostly appears normal, however one beat is followed instantly by another beat, and then an irregular gap. (extra heart beat)
referring to its structure, explain how haemoglobin combines with oxygen
Hb has 4 polypeptide chains; each chain is bound to a haem prosthetic group containing iron (Fe2+)
- each Fe group combines with one oxygen molecule (reversible)
Hb + 4O2 -> Hb(O2)4
explain the sigmoid curve produced in an oxygen dissociation curve.
as the partial pressure of oxygen increases, saturation of Hb increases.
at low po2, affinity for oxygen is low
- at higher po2, oxygen mol binds to Hb molecule, changing its quaternary structure, making it more easily bind to another oxygen molecule
explain why the 4th oxygen molecule binds to Hb at only a slightly higher po2.
when Hb is 75% saturated, the chances of a collision are lowered due to being almost fully saturated. therefore, increasing the pressure doesn’t have much impact