Module 13 Flashcards
Population
Groups of individuals of a species which occupy the same physical space and interbreed
Gene Pool
All alleles of every gene in a population
Organismal Polymorphism
Variation of traits within a population (2+ alleles present in a pop.)
Single Nucleotide Polymorphism (SNPs)
Single base pair changes in DNA, responsible for the majority of genetic variation (ex. beta-globin gene in humans)
Allele Frequency
(# of copies of an allele in a population) / (total # alleles for the gene)
Genotype Frequency
(# individuals with a particular genotype) / (total # individuals within a population)
Hardy Weinberg Equation
p2 + 2pq + q2
Hardy Weinberg Equation Assumptions
- No mutations
- No drift
- No migration
- No natural selection
- Random mating
“No mutts, drifting, migraines, natural soils, just regular moles”
Microevolution is governed by:
- Mutation
- Genetic drift
- Gene flow (migration)
- Natural selection
- Nonrandom mating
4 Patterns of Natural Selection
- Directional selection (unidirectional)
- Balancing selection (2 or more alleles, heterozygote advantage)
- Disruptive (bidirectional)
- Stabilizing (single phenotype)
Mean Fitness of a Population (w)
w = p2wAA + 2pqwAa + q2waa
Selection Coefficient (s) for Heterozygote Advantage
s = 1 - w
Genetic Drift
A change in genetic variation due to chance (ex. bottleneck, founder effects)
Migration (Gene Flow)
Transfer of alleles from donor population to recipient, changing its gene pool and forming a “conglomerate”
To calculate conglomerate allele frequencies, we must know ____ and ____
original allele freqs. for both donor and recipient pops., proportion of conglomerate pop. due to migrants
Bidirectional migration ____ allele frequency differences between populations, can ____ genetic diversity within a population
reduces, enhance
Assortative Mating
Individuals do not mate randomly, can be positive (similar) or negative (dissimilar)
Inbreeding
Reproduction between two genetically related individuals (can result in inbreeding depression and extinction vortex)