Module 11 : Pulmonary Hypertension Flashcards
what is pulmonary hypertension characterized by
- elevated pulmonary arterial pressures secondary to RV failure
how are the categories of pulmonary hypertension characterized
- based on which area of the circulatory system they affect which increased the pulmonary pressure
what is pulmonary HTN
- increased pressure in the pulmonary vasculature
what is pulmonary HTN defined as
- PCWP > 15mmHg
- SPAP = RVSP if no RVOT obstruction 30-35
- MPAP >/= 35mmHg
- PVR >/= 3 wood units
what will be the respiratory symptoms of PHTN
- shortness of breath
- cough
- wheezing
- hemoptysis
- intercostal retraction
what are the 4 signs of right heart failure
- jugular venous congestion
- peripheral edema
- ascites
- hepatosplenomegaly
what are 5 associated cardiac symptoms with PHTN
- palpitations/arrhtymias
- chest pain
- shortness of breath on exertion
- othropnea
- syncope
what is normal RA and IVC pressure
0-4mmHg (average)
what is normal right ventricle systolic and diastolic pressure
< 25 / < 10
what is normal pulmonary artery systolic and diastolic pressure
< 25 / < 10
how do we calculate RVSP with RAP and TV pg
RVSP = RAP + TVpg
what is the RAP
RA pressure from IVC diameter
- 3,8,15
what is the TV pg
- tricuspid valve pressure gradient
- reflects the difference in pressure between RA and RV
what RVSP would indicate mild moderate or severe PHTN
< 30 mmHg
30-35 mmHg
> 35 mmHg
what is normal TR velocity
< 2.8-2.9 m/s
what are the 6 cardiac causes of right sided heart failure
- left sided heart failure is most common
- pulmonic valve stenosis
- right ventricular infarction
- massive TR
- congenital malformation
- shunts
what are the 2 categories of pulmonary causes of right heart failure
- parenchymal
- vascular disease
what are the 5 parenchymal causes of elevated right heart pressure
- COPD asthma
- interstitial lung disease
- adult respiratory distress syndrome
- chronic lung infection
what are the 2 vascular causes of right heart pressure increase
- pulmonary embolism
- primary pulmonary hypertension
how does left sided heart failure increase right heart pressure
- retrograde increased load/pressure
+ LV>LA>PLM VASC>RV>RA>IVC
why does cor pulmonale occur
- increased resistance in the pulmonary circulation
what is the pathophysiology of cor pulmonale
- progressively increasing chronic pressure overload of the right ventricle as it ejects into the high resistance vascular bed
+ if slow and gradual will first lead ti RV hypertrophy
+ if fast then RV dilation will happen first
+ then RV failure occurs
what is an acute pulmonary embolism most often caused by
- deep vein thrombosis
how is PE and DVT treated
- PE = treat DVT or lung resection
- DVT = IVC filter
what is eisenmengers syndrome
- shunt reversal in patients with significant shunt that have developed PHTN from the shunt
- shunt goes right to left
what 3 things does chronic elevation of RT heart pressures lead to
- dilated coronary sinus
- reopening of PFO
- dilated main PA