Module 1 - Mammalian Urinary System Flashcards
Functional unit of the kidneys
Nephron
The following are functions of the urinary system
A. Balances the water and electrolyte components of the body
B. Helps in production of glucose
C. Both A and B
D. None of the above
C. Both A and B
Two parts of nephron
Glomerulus and Long Tubules
Other name for Long tubules
Renal Tubules
It is responsible for Reabsorption and Secretion processes
Long tubules (renal tubules)
Responsible for filtration
Glomerulus
Glomerulus are made up of _________
Glomerular capillaries (tuft)
Kidney capillary pores are described as ______
Fenestrae
Two groups of capillaries in the kidney
Glomerular and Peritubular
This group of capillary in the kidney is also known as high pressure capillary bed
Glomerular capillaries
This group of capillary in the kidney operates under low pressure
Peritubular capillaries
Flow of process of the urine
A. Reabsorption, Filtration, Secretion, Excretion
B. Secretion, Filtration, Reabsorption, Excretion
C. Filtration, Reabsorption, Secretion, Excretion
D. Filtration, Secretion, Reabsorption, Excretion
C. Filtration, Reabsorption, Secretion, Excretion
Efferent arteriole leads to what group of capillaries
Peritubular capillaries
First stage in the formation of urine
Glomerular Filtration
Product of glomerular filtration
glomerular filtrate
GFR of Glomerular Hydrostatic Pressure
60 mmHg
GFR of Plasma Colloid Osmotic Pressure
32 mmHg
GFR of Bowman’s Capsule pressure
18 mmHg
GFR of Bowman’s Capsule Osmotic Pressure
10 mmHg
It supplies blood to the kidneys
Renal artery
These are the extensions of peritubular capillaries
Vasa recta
Two types of mechanism
Afferent arteriolar mechanism
Efferent arteriolar mechanism
The arterioles can constrict due to the stimulation of _______ , thus decreases the blood flow and the GFR
Sympathetic nerve fiber
Sympathetic nerve fiber activity is triggered by a vasoconstrictor substance called
Angiotensin II
Are present in the walls of afferent and efferent arterioles
Juxtaglomerular cells
Its cells are in the initial portion of distal tubules, but come in contact with the cells of afferent and efferent arterioles
Macula Densa
Juxtaglomerular complex is stimulated by _________
A. Increase HCO3- in the Macula Densa
B. Increase NaCl in the Macula Densa
C. Decrease HCO3- in the Macula Densa
D. Decrease NaCl in the Macula Densa
E. Decrease K
D. Decrease NaCl in the Macula Densa
Decreased NaCl in the macula densa causes the dilation of ____________
A. Dilation of Afferent arteriole
B. Dilation of Efferent arteriole
C. Both A and B
C. Both A and B
The dilation causes the release of _______
Renin
When dilation occurs, it causes to release Renin which then acts on ________
Angiotensinogen to form Angiotensin I
A potent vasoconstrictor causes ________ and ________
A. Constriction : Afferent arteriolar resistance
B. Constriction : Efferent resistance
C. Dilation : Afferent arteriolar resistance
D. Dilation : Efferent resistance
E. Constriction : Afferent and Efferent Resistance
F. Dilation : Afferent and Efferent Resistance
E. Constriction : Afferent and Efferent Resistance
True or False: Angiotensin II stimulates aldosterone secretion from the adrenal glands
True
True or False: Angiotensin II causes vasoconstriction of afferent arterioles
False, it should be efferent arterioles
Angiotensin II stimulates aldosterone secretion from the adrenal glands, which in turn, cause an increase __________ reabsorption from the renal tubules.
Sodium NaCl
Give at least 3 substances that cannot/should not be seen in urine
protein, glucose, amino acid, vitamins
aceto/acetate ions
Glucose in the urine is a sign of
Diabetes
term for Formation of glucose
Gluconeogenesis
It is also known as the terminal part
Renal pelvis
Increase of sodium concentration in the ECF is due to ____________
Increase in sodium retention
An increase in sodium retention increases the sodium concentration in the ECF, leading to an ____________
Increase in osmolality of the blood
Increase in osmolality of the blood also means that there is an _________
ECF water deficit
6 classes of urine
Diluted, Non diluted, hypertonic, hypotonic, acidic, alkaline
It is an antidiuretic hormone (ADH) which favors the reabsorption of more water in the tubules of the nephron
Vasopressin
Intracellular dehydration can send stimulus to posterior pituitary gland to release ________
Vasopressin
Parts of mammalian renal tubules
Proximal (convoluted) tubule
Loop of henle (descending and ascending)
Distal tubule (early and late)
Cortical collecting tubule
Medullary collecting duct
Renal pelvis
Shape of mammalian kidney
bean shaped
Location of mammalian kidney
Bilaterally located in the retro peritoneal cavity
Is the osmolar concentration expressed as osmoles per liter of solution
Osmolarity
The reason why there is reabsorption of water from distal tubule
Antidiuretic hormone
reabsorbs sodium from the lumen and secrete potassium ions into the lumen
principal cells
reabsorbs potassium ions and bicarbonate ions from the lumen and secrete hydrogen ions into the lumen
intercalated cells
released when there is increase osmolality of the plasma
Vasopressin
solves the increase of salt concentration
renin angiotensin aldosterone system (RAAS)
Aldosterone reabsorbs _______ and secretes ______
NaCl & H20 : K
Normal composition of ECF
I. Less amount of Sodium, Chloride, Bicarbonate
II. Large amount of Potassium, Magnesium, Phosphate
III. Large amount of Sodium, Chloride, Bicarbonate
IV. Less amount of Potassium, Magnesium, Phosphate
A. Both I and II
B. Both III and I
C. Both III and IV
C. Both III and IV
What is the NEXT process when substances are to be excreted out of renal pelvis as part of urine components into the ureter
Temporarily stores in urinary bladder
What do you call this process where substances from the lumen move out to the ECF thru diffusion or active transport processes
Reabsorption
Contains high salt, less water
Hypertonic urine
Contains less salt but high in water
Hypotonic urine
More solutes, less solvent
Concentrated urine
More water, less solutes
Diluted urine
more hydrogen ions, less bicarbonate ions
acidic urine
When Hypo/Hypertonic urine is stimulated by the alteration of salt content in the e plasma which eventually passes through the distal tubule to affect the JG complex, it causes _______________
activation or inhibition of renin-angiotensin II mechanism
The one that stimulates the release of aldosterone by the adrenal glands
Angiotensin II
Animal with transparency urine
Horse
Urea is formed by what organ
Liver
Urea is formed by the liver from ammonia which is produced during __________________
amino acid metabolism
type of urine of herbivorous animals
alkaline/basic
characteristic of urethral canal of oxens
directed toward the ground
A surgical procedure to remove a part of kidney
Nephrectomy